Evidence map›Paper›PMID 25927270›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2015

Maternal serum markers, characteristics and morbidly adherent placenta in women with previa.

D J Lyell, A M Faucett, R J Baer, Y J Blumenfeld, M L Druzin, Y Y El-Sayed, G M Shaw, R J Currier, L L Jelliffe-Pawlowski

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 57 citations in OpenAlex.

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  15. Pre-pregnancy or first-trimester risk scoring to identify women at high risk of preterm birth.European journal of obstetrics, gynecology, and reproductive biology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

D J LyellDepartment of Obstetrics and Gynecology, Stanford University, Stanford, CA, USA.
A M FaucettDepartment of Obstetrics and Gynecology, University of Colorado Denver, Aurora, CO, USA.
R J BaerGenetic Disease Screening Program, California Department of Public Health, Richmond, CA, USA.
Y J BlumenfeldDepartment of Obstetrics and Gynecology, Stanford University, Stanford, CA, USA.
M L DruzinDepartment of Obstetrics and Gynecology, Stanford University, Stanford, CA, USA.
Y Y El-SayedDepartment of Obstetrics and Gynecology, Stanford University, Stanford, CA, USA.
G M ShawDepartment of Pediatrics, Stanford University, Stanford, CA, USA.
R J CurrierGenetic Disease Screening Program, California Department of Public Health, Richmond, CA, USA.
L L Jelliffe-Pawlowski1] Genetic Disease Screening Program, California Department of Public Health, Richmond, CA, USA [2] Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, USA.
Stanford University · USCalifornia Department of Public Health · USUniversity of California, San Francisco · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine associations with morbidly adherent placenta (MAP) among women with placenta previa. STUDY

designWomen with MAP (cases) and previa alone (controls) were identified from a cohort of 236,714 singleton pregnancies with both first and second trimester prenatal screening, and live birth and hospital discharge records; pregnancies with aneuploidies and neural tube or abdominal wall defects were excluded. Logistic binomial regression was used to compare cases with controls.

resultIn all, 37 cases with MAP and 699 controls with previa alone were included. Risk for MAP was increased among multiparous women with pregnancy-associated plasma protein-A (PAPP-A) ⩾95th percentile (⩾2.63 multiple of the median (MoM); adjusted OR (aOR) 8.7, 95% confidence interval (CI) 2.8 to 27.4), maternal-serum alpha fetoprotein (MS-AFP) ⩾95th percentile (⩾1.79 MoM; aOR 2.8, 95% CI 1.0 to 8.0), and 1 and ⩾2 prior cesarean deliveries (CDs; aORs 4.4, 95% CI 1.5 to 13.6 and 18.4, 95% CI 5.9 to 57.5, respectively).

conclusionElevated PAPP-A, elevated MS-AFP and prior CDs are associated with MAP among women with previa.

Indexed as

AdolescentAdultalpha-FetoproteinsBiomarkersCaliforniaCesarean SectionFemaleHumansLogistic ModelsPlacenta AccretaPlacenta PreviaPregnancyPregnancy-Associated Plasma Protein-APregnancy ComplicationsPregnancy Trimester, FirstPregnancy Trimester, Secondalpha-FetoproteinsBiomarkersPregnancy-Associated Plasma Protein-A

Identifiers

PMID25927270
OpenAlexW2040553335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.