Evidence map›Paper›PMID 25927010›Full record

ArticleAntibiotics (Basel, Switzerland)2015

Mechanisms of Antimicrobial Peptide Resistance in Gram-Negative Bacteria.

Victor I Band, David S Weiss

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Adaptive Response ofAntibiotics (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Antimicrobial peptides in post-harvest management of fruits.Journal of food science and technology · 2025
    Review
  13. Article
  14. Editorial: Developing therapeutics for antimicrobial resistant pathogens: volume II.Frontiers in cellular and infection microbiology · 2025
    Article
  15. Review
  16. Channeling kynurenine.Nature chemical biology · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Victor I BandDepartment of Microbiology and Immunology, Emory University, Atlanta, GA 30329, USA ; Yerkes Primate Research Center, Emory University, Atlanta, GA 30329, USA ; Emory Vaccine Center, Emory University, Atlanta, GA 30329, USA.
David S WeissYerkes Primate Research Center, Emory University, Atlanta, GA 30329, USA ; Emory Vaccine Center, Emory University, Atlanta, GA 30329, USA ; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30329, USA.

Funding

ArmR: a novel drug target and mediator of antibiotic resistanceR33AI098800 · NIAID · EMORY UNIVERSITY · PI WEISS, DAVID S · 2014 to 2016
$1.6M
NIAID NIH HHS R33 AI098800
6 · The paper itself

Abstract

Cationic antimicrobial peptides (CAMPs) are important innate immune defenses that inhibit colonization by pathogens and contribute to clearance of infections. Gram-negative bacterial pathogens are a major target, yet many of them have evolved mechanisms to resist these antimicrobials. These resistance mechanisms can be critical contributors to bacterial virulence and are often crucial for survival within the host. Here, we summarize methods used by Gram-negative bacteria to resist CAMPs. Understanding these mechanisms may lead to new therapeutic strategies against pathogens with extensive CAMP resistance.

Indexed as

AMPantibiotic resistanceantimicrobial peptideCAMPGram-negative

Identifiers

PMID25927010
PMCPMC4410734

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.