ReviewGastroenterology and hepatology from bed to bench2015
Th17, intestinal microbiota and the abnormal immune response in the pathogenesis of celiac disease.
Review in Gastroenterology and hepatology from bed to bench, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- The Effects of a Gluten-Free Diet on Immune Markers and Kynurenic Acid Pathway Metabolites in Patients With Schizophrenia Positive for Antigliadin Antibodies Immunoglobulin G.Journal of clinical psychopharmacologyTrial
- HFD aggravated the arthritis and atherosclerosis by altering the intestinal status and gut microbiota.Molecular medicine (Cambridge, Mass.) · 2024Article
- Duodenal transcriptomics demonstrates signatures of tissue inflammation and immune cell infiltration in children with environmental enteric dysfunction across global centers.The American journal of clinical nutrition · 2024Article
- Shared and distinct genetics of pure type 1 diabetes and type 1 diabetes with celiac disease, homology in their auto-antigens and immune dysregulation states: a study from North India.Acta diabetologica · 2024Article
- Microbiota Therapy in Inflammatory Bowel Disease.Visceral medicine · 2024Review
- Prevalence of fungal colonization among patients with psoriasis in difficult-to-treat areas: impact of apremilast on mycotic burden and clinical outcomes.Frontiers in immunology · 2024Article
- The relationship of peripheral inflammation with antibodies to gliadin (AGA IgG) in persons with schizophrenia.Schizophrenia research · 2023Article
- Introducing New Potential Biomarkers for Celiac Disease among the Genes Extracted from General Databases.Middle East journal of digestive diseases · 2022Article
- The Multiomics Analyses of Fecal Matrix and Its Significance to Coeliac Disease Gut Profiling.International journal of molecular sciences · 2021Review
- Skin and Gut Microbiome in Psoriasis: Gaining Insight Into the Pathophysiology of It and Finding Novel Therapeutic Strategies.Frontiers in microbiology · 2020Review
- Coeliac Disease and Mast Cells.International journal of molecular sciences · 2019Review
- Inhibition of immune checkpoints prevents injury-induced heterotopic ossification.Bone research · 2019Article
- One Health, Fermented Foods, and Gut Microbiota.Foods (Basel, Switzerland) · 2018Review
- Prevalence of celiac disease serological markers in a cohort of Italian rheumatological patients.Gastroenterology and hepatology from bed to bench · 2018Article
- HLA Typing and Celiac Disease in Moroccans.Medical sciences (Basel, Switzerland) · 2017Article
- Immunopathogenesis and therapeutic approaches in pediatric celiac disease.Expert review of clinical immunology · 2016Review
- Article
- Strain-level dissection of the contribution of the gut microbiome to human metabolic disease.Genome medicine · 2016Review
- Gluten free diet is a cure not a poison!Gastroenterology and hepatology from bed to bench · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Celiac disease (CD) is an autoimmune enteropathy induced by the ingestion of gluten in genetically predisposed individuals who carry the HLA-DQ2 or -DQ8 alleles. The immune response is abnormal in celiac disease with small intestinal epithelial damage via CD8+CD4- intraepithelial lymphocytes. The etiology is multifactorial involving genetic and environmental factors, an abnormal immune response, and intestinal dysbiosis. The innate and acquired T-cell mediated immunity play important roles in the pathogenesis of this disease, particularly CD4+ Th17 cells, which have been shown to have critical functions in host defense against bacterial pathogens and in the inflammatory responses to deamidated gluten peptides. We review what is known about the interaction between immune system and intestinal microbiota in the pathogenesis of celiac disease.
Indexed as
Identifiers
25926936PMC4404588W1498138199What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.