ArticleFrontiers in microbiology2015
Application of swine manure on agricultural fields contributes to extended-spectrum β-lactamase-producing Escherichia coli spread in Tai'an, China.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Transmission routes of antibiotic resistant bacteria: a systematic review.BMC infectious diseases · 2022Pooled it
- Antibiotic resistance of fecal carriage of Escherichia coli from pig farms in China: a meta-analysis.Environmental science and pollution research international · 2022Pooled it
- Dairy manure, glyphosate, and antimicrobials (copper, streptomycin, and triazole) modulated the composition of antimicrobial resistance at the gene and microbial levels in a processing tomato field.Microbiology spectrum · 2026Article
- Integrated Phenotypic and Genomic Characterization of Cefotaxime/Clavulanic Acid Inhibitor-Positive Multidrug-ResistantAnimals : an open access journal from MDPI · 2026Article
- Whole genome analysis reveals the distribution and diversity of plasmid reservoirs of NDM and MCR in commercial chicken farms in China.Microbiology spectrum · 2025Article
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- Current epidemiologic features and health dynamics of ESBL-producingBiosafety and health · 2024Review
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- Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations.Molecular biology and evolution · 2023Article
- Detection and characterization of ESBL-producingPeerJ · 2022Article
- On-Farm Anaerobic Digestion of Dairy Manure Reduces the Abundance of Antibiotic Resistance-Associated Gene Targets and the Potential for Plasmid Transfer.Applied and environmental microbiology · 2021Article
- Article
- A Large Spatial Survey of Colistin-Resistant GeneMicroorganisms · 2021Article
- Occurrence and characteristics of Escherichia coli mcr-1-like in rabbits in Shandong, China.Veterinary medicine and science · 2021Article
- Extended-spectrum β-lactamase-producing Escherichia coli isolated from raw vegetables in South Korea.Scientific reports · 2020Article
- Bacteriophage-Induced Lipopolysaccharide Mutations inAntibiotics (Basel, Switzerland) · 2020Article
- Enterococci, from Harmless Bacteria to a Pathogen.Microorganisms · 2020Review
- Proteomic analysis of ESBL-producing Escherichia coli under bentonite condition.Environmental science and pollution research international · 2019Article
- Prevalence of Antibiotic Resistance Genes in Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2019Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (E. coli) is increasing rapidly in both hospital environments and animal farms. A lot of animal manure has been directly applied into arable fields in developing countries. But the impact of ESBL-positive bacteria from animal manure on the agricultural fields is sparse, especially in the rural regions of Tai'an, China. Here, we collected 29, 3, and 10 ESBL-producing E. coli from pig manure, compost, and soil samples, respectively. To track ESBL-harboring E. coli from agricultural soil, these isolates of different sources were analyzed with regard to antibiotic resistance profiles, ESBL genes, plasmid replicons, and enterobacterial repetitive intergenic consensus (ERIC)-polymerase chain reaction (PCR) typing. The results showed that all the isolates exhibited multi-drug resistant (MDR). CTX-M gene was the predominant ESBL gene in the isolates from pig farm samples (30/32, 93.8%) and soil samples (7/10, 70.0%), but no SHV gene was detected. Twenty-five isolates contained the IncF-type replicon of plasmid, including 18 strains (18/32, 56.3%) from the pig farm and 7 (7/10, 70.0%) from the soil samples. ERIC-PCR demonstrated that 3 isolates from soil had above 90% genetic similarity with strains from pig farm samples. In conclusion, application of animal manure carrying drug-resistant bacteria on agricultural fields is a likely contributor to antibiotic resistance gene spread.
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