ArticleFrontiers in systems neuroscience2015
Systems approach to the study of brain damage in the very preterm newborn.
Article in Frontiers in systems neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 21 citations in OpenAlex.
- Neonatal inflammation predicts adolescent brain volume and neurologic outcomes in children born extremely prematurely.Scientific reports · 2026Article
- Review
- A multi-omic approach identifies an autism spectrum disorder (ASD) regulatory complex of functional epimutations in placentas from children born preterm.Autism research : official journal of the International Society for Autism Research · 2023Article
- Metal mixtures modeling identifies birth weight-associated gene networks in the placentas of children born extremely preterm.Chemosphere · 2023Article
- Galantamine ameliorates hyperoxia-induced brain injury in neonatal mice.Frontiers in neuroscience · 2023Article
- The placenta epigenome-brain axis: placental epigenomic and transcriptomic responses that preprogram cognitive impairment.Epigenomics · 2022Article
- Altered Cerebral Curvature in Preterm Infants Is Associated with the Common Genetic Variation Related to Autism Spectrum Disorder and Lipid Metabolism.Journal of clinical medicine · 2022Article
- The Global Pregnancy Collaboration (CoLab) symposium on short- and long-term outcomes in offspring whose mothers had preeclampsia: A scoping review of clinical evidence.Frontiers in medicine · 2022Article
- Measuring Cot-Side the Effects of Parenteral Nutrition on Preterm Cortical Function.Frontiers in human neuroscience · 2020Article
- The Absence of TLR4 Prevents Fetal Brain Injury in the Setting of Intrauterine Inflammation.Reproductive sciences (Thousand Oaks, Calif.) · 2019Article
- Microorganisms in the Placenta: Links to Early-Life Inflammation and Neurodevelopment in Children.Clinical microbiology reviews · 2019Review
- Polygenic risk for neuropsychiatric disease and vulnerability to abnormal deep grey matter development.Scientific reports · 2019Article
- Elevated protein concentrations in newborn blood and the risks of autism spectrum disorder, and of social impairment, at age 10 years among infants born before the 28th week of gestation.Translational psychiatry · 2018Observational
- Circulating biomarkers in extremely preterm infants associated with ultrasound indicators of brain damage.European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2018Observational
- Machine learning shows association between genetic variability inProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes.PloS one · 2017Article
- Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants.Brain and behavior · 2016Article
- The Development of Extremely Preterm Infants Born to Women Who Had Genitourinary Infections During Pregnancy.American journal of epidemiology · 2016Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 5 countries.
Funding
Abstract
backgroundA systems approach to the study of brain damage in very preterm newborns has been lacking.
methodsIn this perspective piece, we offer encephalopathy of prematurity as an example of the complexity and interrelatedness of brain-damaging molecular processes that can be initiated inflammatory phenomena.
resultsUsing three transcription factors, nuclear factor-kappa B (NF-κB), Notch-1, and nuclear factor erythroid 2 related factor 2 (NRF2), we show the inter-connectedness of signaling pathways activated by some antecedents of encephalopathy of prematurity.
conclusionsWe hope that as biomarkers of exposures and processes leading to brain damage in the most immature newborns become more readily available, those who apply a systems approach to the study of neuroscience can be persuaded to study the pathogenesis of brain disorders in the very preterm newborn.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.