ArticleBiology letters2015
Oxygen supply limits the heat tolerance of lizard embryos.
Article in Biology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Heat-Induced Hatching: Clarifying Effects of Hydration and Heating Rate on Behavioral Thermal Tolerance of Red-Eyed Treefrog Embryos.Integrative organismal biology (Oxford, England) · 2025Article
- Rapid heat hardening in embryos of the lizardBiology letters · 2023Article
- A review of the effects of incubation conditions on hatchling phenotypes in non-squamate reptiles.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2022Review
- Heat-Induced Hatching of Red-Eyed Treefrog Embryos: Hydration and Clutch Structure Increase Behavioral Thermal Tolerance.Integrative organismal biology (Oxford, England) · 2022Article
- Environmental Thermal Stress Induces Neuronal Cell Death and Developmental Malformations in Reptiles.Integrative organismal biology (Oxford, England) · 2021Article
- The effect of respiratory gases and incubation temperature on early stage embryonic development in sea turtles.PloS one · 2020Article
- Oxygen supply limits the heat tolerance of avian embryos.Biology letters · 2019Article
- Adaptive responses of the embryos of birds and reptiles to spatial and temporal variations in nest temperatures.Proceedings. Biological sciences · 2019Review
- Pregnancy reduces critical thermal maximum, but not voluntary thermal maximum, in a viviparous skink.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2019Article
- Maternal corticosterone increases thermal sensitivity of heart rate in lizard embryos.Biology letters · 2019Article
- Transient window of resilience during early development minimizes teratogenic effects of heat in zebrafish embryos.Developmental dynamics : an official publication of the American Association of Anatomists · 2018Article
- A positive genetic correlation between hypoxia tolerance and heat tolerance supports a controversial theory of heat stress.Biology letters · 2017Article
- More oxygen during development enhanced flight performance but not thermal tolerance of Drosophila melanogaster.PloS one · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanisms that set the thermal limits to life remain uncertain. Classically, researchers thought that heating kills by disrupting the structures of proteins or membranes, but an alternative hypothesis focuses on the demand for oxygen relative to its supply. We evaluated this alternative hypothesis by comparing the lethal temperature for lizard embryos developing at oxygen concentrations of 10-30%. Embryos exposed to normoxia and hyperoxia survived to higher temperatures than those exposed to hypoxia, suggesting that oxygen limitation sets the thermal maximum. As all animals pass through an embryonic stage where respiratory and cardiovascular systems must develop, oxygen limitation may limit the thermal niches of terrestrial animals as well as aquatic ones.
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