ArticleEuropean child & adolescent psychiatry2016
Identifying children and adolescents at ultra high risk of psychosis in Italian neuropsychiatry services: a feasibility study.
Article in European child & adolescent psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 8 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 8 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Negative symptoms in children and adolescents with early-onset psychosis and at clinical high-risk for psychosis: systematic review and meta-analysis.The British journal of psychiatry : the journal of mental science · 2023Pooled it
- Prognostic accuracy and clinical utility of psychometric instruments for individuals at clinical high-risk of psychosis: a systematic review and meta-analysis.Molecular psychiatry · 2022Pooled it
- Negative Prognostic Effect of Baseline Antipsychotic Exposure in Clinical High Risk for Psychosis (CHR-P): Is Pre-Test Risk Enrichment the Hidden Culprit?The international journal of neuropsychopharmacology · 2021Pooled it
- Establishing a clinical service to prevent psychosis: What, how and when? Systematic review.Translational psychiatry · 2021Pooled it
- Comorbid Personality Disorders in Individuals With an At-Risk Mental State for Psychosis: A Meta-Analytic Review.Frontiers in psychiatry · 2019Pooled it
- Clinical high risk for psychosis in children and adolescents: a systematic review.European child & adolescent psychiatry · 2018Pooled it
- Can We Predict Psychosis Outside the Clinical High-Risk State? A Systematic Review of Non-Psychotic Risk Syndromes for Mental Disorders.Schizophrenia bulletin · 2018Pooled it
- The Dark Side of the Moon: Meta-analytical Impact of Recruitment Strategies on Risk Enrichment in the Clinical High Risk State for Psychosis.Schizophrenia bulletin · 2016Pooled it
- Annual Research Review: Psychosis in children and adolescents: key updates from the past 2 decades on psychotic disorders, psychotic experiences, and psychosis risk.Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- Network analysis of inflammation and symptoms in recent onset schizophrenia and the influence of minocycline during a clinical trial.Translational psychiatry · 2023Article
- Neurocognition and functioning in adolescents at clinical high risk for psychosis.Child and adolescent psychiatry and mental health · 2023Article
- Behavioral problems in psychotic, clinically high-risk, and non-psychotic adolescent patients.Annals of general psychiatry · 2022Article
- Prognostic Accuracy of DSM-5 Attenuated Psychosis Syndrome in Adolescents: Prospective Real-World 5-Year Cohort Study.Schizophrenia bulletin · 2021Article
- ITAlian partnership for psychosis prevention (ITAPP): Improving the mental health of young people.European psychiatry : the journal of the Association of European Psychiatrists · 2021Article
- Screening of the college students at clinical high risk for psychosis in China: a multicenter epidemiological study.BMC psychiatry · 2021Article
- Clinical features of adolescents diagnosed with eating disorders and at risk for psychosis.European psychiatry : the journal of the Association of European Psychiatrists · 2020Article
- DSM-5 Attenuated Psychosis Syndrome in Adolescents Hospitalized With Non-psychotic Psychiatric Disorders.Frontiers in psychiatry · 2020Article
- The Critical Need for Help-Seeking Controls in Clinical High-Risk Research.Clinical psychological science : a journal of the Association for Psychological Science · 2019Article
- Clinical high risk for psychosis in childhood and adolescence: findings from the 2-year follow-up of the ReARMS project.European child & adolescent psychiatry · 2019Article
- Pan-London Network for Psychosis-Prevention (PNP).Frontiers in psychiatry · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The past 20 years have seen the evolution of the construct of a clinical high-risk (hereafter, HR) state for psychosis. This construct is designed to capture the pre-psychotic phase. Some aspects of this approach, such as its feasibility in children and adolescents, are still under investigation. In the present study, we address the feasibility of implementing prodrome clinics for HR individuals within the framework of Italy's national child and adolescent neuropsychiatry services and the clinical relevance of a HR diagnosis in this population. Using the Comprehensive Assessment of At-Risk Mental States (CAARMS) to identify help-seeking patients meeting at least one HR criterion at baseline (HR+), we recruited 50 subjects for a feasibility study. The results obtained show that the Italian version of the CAARMS is easily administrable, causing patients no substantial discomfort. The prevalence of HR+ in our cohort was 44 %, which increased by an additional 18 % when negative symptoms were considered as an experimental inclusion criterion (HRNeg). The HR+ subjects were significantly more impaired in their social and occupational functioning than their HR- peers (subjects not at HR). The cumulative 1-year transition risk of psychosis of the HR+ group was 26.7 %. When the HRNeg group was added, the 1-year transition risk was 17.3 %. We suggest that administration of the CAARMS to children and adolescents with putative prodromal psychosis is feasible and that this assessment can easily be integrated into existing Italian neuropsychiatry services although clinicians should interpret results with caution as results in this age group still have to be replicated.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.