Evidence map›Paper›PMID 25925679›Full record

ArticleScience translational medicine2015

Renal denervation: Not as easy as it looks.

Murray Esler

Abstract readComment
PubMed Publisher
In one paragraph

Article in Science translational medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Renal denervation for resistant hypertension.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Renal denervation for resistant hypertension.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Review
  4. Review
  5. Renal Denervation for the Hypertension of Chronic Kidney Disease: A Special Case?Journal of clinical hypertension (Greenwich, Conn.) · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Murray EslerBaker IDI Heart and Diabetes Institute, Post Office Box 6492, St. Kilda Road Central, Melbourne, Victoria, Australia.
Baker Heart and Diabetes Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal sympathetic denervation with intravascular radiofrequency catheters in hypertensive patients is less effective than anticipated, owing to radio frequency energy being applied to a part of the renal artery where the nerves are at the greatest distance from the aortic lumen and to distortion of energy distribution and temperature gradients by regional tissue anatomical variations (Tzafriri et al., this issue).

Indexed as

DenervationAnimalsArteriesHypertensionKidney

Identifiers

PMID25925679
OpenAlexW2120012137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.