ArticleMedical science monitor basic research2015
Molluscs as models for translational medicine.
Article in Medical science monitor basic research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Article
- First evidence of an anxiety-like behavior and its pharmacological modulation in a molluscan model organism, Lymnaea stagnalis.Translational psychiatry · 2025Article
- Use of invertebrates to model chemically induced parkinsonism-symptoms.Biochemical Society transactions · 2023Review
- Identification and characterization of the kynurenine pathway in the pond snail Lymnaea stagnalis.Scientific reports · 2022Article
- Comparative analysis of novel and common reference genes in adult tissues of the mussel Mytilus galloprovincialis.BMC genomics · 2022Article
- A flavonoid, quercetin, is capable of enhancing long-term memory formation if encountered at different times in the learning, memory formation, and memory recall continuum.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2022Article
- Article
- What can we teach Lymnaea and what can Lymnaea teach us?Biological reviews of the Cambridge Philosophical Society · 2021Review
- To eat or not to eat: a Garcia effect in pond snails (Lymnaea stagnalis).Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2021Article
- Mobilizing molluscan models and genomes in biology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- The pond snail Lymnaea stagnalis.EvoDevo · 2020Review
- Calcium-Binding Proteins in the Nervous System during Hibernation: Neuroprotective Strategies in Hypometabolic Conditions?International journal of molecular sciences · 2019Review
- Hibernation induces changes in the metacerebral neurons of Cornu aspersum: distribution and co-localization of cytoskeletal and calcium-binding proteins.Invertebrate neuroscience : IN · 2018Article
- An adaptable chromosome preparation methodology for use in invertebrate research organisms.BMC biology · 2018Article
- Co-Expression Analysis of Blood Cell Genome Expression to Preliminary Investigation of Regulatory Mechanisms in Uremia.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- Identification of miRNA/mRNA-Negative Regulation Pairs in Nasopharyngeal Carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper describes the advantages of adopting a molluscan model for studying the biological basis of some central nervous system pathologies affecting humans. In particular, we will focus on the freshwater snail Lymnaea stagnalis, which is already the subject of electrophysiological studies related to learning and memory, as well as ecotoxicological studies. The genome of L. stagnalis has been sequenced and annotated but the gene characterization has not yet been performed. We consider the characterization of the gene networks that play crucial roles in development and functioning of the central nervous system in L. stagnalis, an important scientific development that comparative biologists should pursue. This important effort would add a new experimental model to the limited number of invertebrates already used in studies of translational medicine, the discipline that seeks to improve human health by taking advantage of knowledge collected at the molecular and cellular levels in non-human organisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.