Evidence map›Paper›PMID 25925572›Full record

ArticleNucleic acids research2015

PolySearch2: a significantly improved text-mining system for discovering associations between human diseases, genes, drugs, metabolites, toxins and more.

Yifeng Liu, Yongjie Liang, David Wishart

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 147 citations in OpenAlex.

  1. Article
  2. Chemical Composition of Commercial Cannabis.Journal of agricultural and food chemistry · 2024
    Article
  3. Review
  4. Article
  5. Efficacy of active ingredients in Qingdai on ulcerative colitis: a network pharmacology-based evaluation.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. PHILM2Web: A high-throughput database of macromolecular host-pathogen interactions on the Web.Database : the journal of biological databases and curation · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Biomedical Literature Mining for Repurposing Laboratory Tests.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
  19. Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yifeng LiuDepartment of Computing Science, University of Alberta, Edmonton, T6G 2E8 Canada.
Yongjie LiangDepartment of Computing Science, University of Alberta, Edmonton, T6G 2E8 Canada.
David WishartDepartment of Computing Science, University of Alberta, Edmonton, T6G 2E8 Canada Department of Biological Science, University of Alberta, Edmonton, T6G 2E6 Canada david.wishart@ualberta.ca.
University of Alberta · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

PolySearch2 (http://polysearch.ca) is an online text-mining system for identifying relationships between biomedical entities such as human diseases, genes, SNPs, proteins, drugs, metabolites, toxins, metabolic pathways, organs, tissues, subcellular organelles, positive health effects, negative health effects, drug actions, Gene Ontology terms, MeSH terms, ICD-10 medical codes, biological taxonomies and chemical taxonomies. PolySearch2 supports a generalized 'Given X, find all associated Ys' query, where X and Y can be selected from the aforementioned biomedical entities. An example query might be: 'Find all diseases associated with Bisphenol A'. To find its answers, PolySearch2 searches for associations against comprehensive collections of free-text collections, including local versions of MEDLINE abstracts, PubMed Central full-text articles, Wikipedia full-text articles and US Patent application abstracts. PolySearch2 also searches 14 widely used, text-rich biological databases such as UniProt, DrugBank and Human Metabolome Database to improve its accuracy and coverage. PolySearch2 maintains an extensive thesaurus of biological terms and exploits the latest search engine technology to rapidly retrieve relevant articles and databases records. PolySearch2 also generates, ranks and annotates associative candidates and present results with relevancy statistics and highlighted key sentences to facilitate user interpretation.

Indexed as

Data MiningDiseaseSoftwareAlgorithmsDatabases, FactualGenesHumansInternetMetabolic Networks and PathwaysPharmaceutical PreparationsPubMedToxins, BiologicalPharmaceutical PreparationsToxins, Biological

Identifiers

PMID25925572
PMCPMC4489268
OpenAlexW1986657538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.