ArticleEuropean radiology2016
Improvement of the accuracy of liver lesion DCEUS quantification with the use of automatic respiratory gating.
Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- A Comprehensive and Repeatable Contrast-Enhanced Ultrasound Quantification Approach for Clinical Evaluations of Tumor Blood Flow.Investigative radiology · 2025Article
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3 authors.
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Abstract
objectivesTo evaluate the efficiency of automatic respiratory gating (ARG) in reducing respiratory motion-induced artefacts from dynamic contrast-enhanced ultrasound (DCEUS) acquisitions and to assess the impact of ARG on DCEUS quantification parameters in patients with liver malignancies.
methodsTwenty-five patients with liver metastasis were imaged with DCEUS. The lognormal indicator dilution model was fitted on time-intensity curves extracted from hepatic lesions with and without the use of ARG and DCEUS quantification parameters were extracted. The goodness of fit was assessed using the coefficient of determination (R (2) LN ). The effect respiration had on the data was assessed using the respiration amplitude (RA) metric. Pearson's correlation coefficient (r) was used to assess the correlation between R (2) LN and RA with and without the use of ARG.
resultsThe RA parameter was strongly correlated with R (2) LN (r = -0.96, P = 7.412 × 10(-15)) and this correlation became weaker with ARG (r = -0.64, P = 5.449 × 10(-4)). ARG significantly influenced the values of the quantification parameters extracted (P ≤ 0.05). The RA was significantly decreased when ARG was used (P = 1.172 × 10(-6)).
conclusionsARG has a significant impact on the quantification parameters extracted and it has been shown to improve the accuracy of liver lesion DCEUS. KEY POINTS: • ARG has a significant impact on DCEUS quantification parameters. • ARG can improve the modelling of liver lesion haemodynamics using DCEUS quantification. • ARG significantly reduces the respiration amplitude of DCEUS lesion time-intensity curves.
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