Evidence map›Paper›PMID 25924994›Full record

ReviewVirologica Sinica2015

Recent advances in the study of Kaposi's sarcoma-associated herpesvirus replication and pathogenesis.

Denis Avey, Brittany Brewers, Fanxiu Zhu

Abstract readReview
In one paragraph

Review in Virologica Sinica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Infection of human induced pluripotent stem cells by an oncogenic herpesvirus.Frontiers in cellular and infection microbiology · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Denis AveyDepartment of Biological Science, Florida State University, Tallahassee, 32306, USA.
Brittany Brewers
Fanxiu Zhu

Funding

Role of KSHV ORF45 in Viral Immune Evasion &ReplicationR01DE016680 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI ZHU, FANXIU · 2005 to 2015
$2.5M
Manipulation of kinase signaling by the human oncovirus KSHVF31CA183250 · NCI · FLORIDA STATE UNIVERSITY · PI AVEY, DENIS · 2014 to 2015
$71k
NCI NIH HHS F31 CA183250NCI NIH HHS F31CA183250NIDCR NIH HHS R01 DE016680NIDCR NIH HHS R01DE016680
6 · The paper itself

Abstract

It has now been over twenty years since a novel herpesviral genome was identified in Kaposi's sarcoma biopsies. Since then, the cumulative research effort by molecular biologists, virologists, clinicians, and epidemiologists alike has led to the extensive characterization of this tumor virus, Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 (HHV-8)), and its associated diseases. Here we review the current knowledge of KSHV biology and pathogenesis, with a particular emphasis on new and exciting advances in the field of epigenetics. We also discuss the development and practicality of various cell culture and animal model systems to study KSHV replication and pathogenesis.

Indexed as

Virus ReplicationAnimalsBiomedical ResearchCell LineCytological TechniquesDisease Models, AnimalEpigenesis, GeneticHerpesvirus 8, HumanHost-Pathogen InteractionsHumansSarcoma, Kaposi

Identifiers

PMID25924994
PMCPMC8200917

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.