Evidence map›Paper›PMID 25923477›Full record

ArticleThe journal of nutrition, health & aging2015

Serum long-chain omega-3 polyunsaturated Fatty acids and future blood pressure in an ageing population.

A N Nyantika, T-P Tuomainen, J Kauhanen, S Voutilainen, J K Virtanen

Open access · greenAbstract read
In one paragraph

Article in The journal of nutrition, health & aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Serum long-chain omega-3 polyunsaturated fatty acids and risk of orthostatic hypotension.Hypertension research : official journal of the Japanese Society of Hypertension · 2016
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

A N NyantikaJyrki K. Virtanen, University of Eastern Finland, Kuopio Campus, Institute of Public Health and Clinical Nutrition, PO Box 1627, 70211 Kuopio, Finland, +358 (0) 294454542 / +358 (0) 403552957 Fax +358-17-162936. E-mail: jyrki.virtanen@uef.fi.
T-P Tuomainen
J Kauhanen
S Voutilainen
J K Virtanen
University of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the associations of serum long-chain omega-3 polyunsaturated fatty acids (PUFA) and hair mercury with future blood pressure in an ageing population.

designProspective study with baseline measurements in 1998-2001 and follow-up measurements in 2005-2008. The linear relationships (β) of baseline serum fatty acids and hair mercury with future systolic and diastolic blood pressure and pulse pressure were analyzed with multiple linear regression models, using log-transformed values.

participants181 men and 200 women aged 53-73 y from the Kuopio Ischemic Heart Disease Risk Factor Study (KIHD) population in Eastern Finland, who were free of cardiovascular disease, diabetes or hypertension at baseline. MEASUREMENTS: Total serum esterified and nonesterified fatty acids and pubic hair mercury were used as markers for exposure. Anthropometric and other lifestyle and health-related data were collected.

resultsThe mean serum concentrations were 1.67% (SD 0.92) for eicosapentaenoic acid (EPA), 0.79% (SD 0.16) for docosapentaenoic acid (DPA) and 2.78 (SD 0.92) for docosahexaenoic acid (DHA), of all serum fatty acids. The mean hair mercury concentration was 1.5 µg/g (SD 1.6). We did not find statistically significant associations between the baseline serum long-chain omega-3 PUFA concentrations or hair mercury content and future blood pressure. Hair mercury did not modify the associations with the long-chain omega-3 PUFAs, either.

conclusionsHigher serum long-chain omega-3 PUFA concentration, a biomarker of fish or fish oil consumption, may not have an impact on future blood pressure in an ageing population.

Indexed as

Blood PressureAgedAgingAnimalsDietDietary FatsDocosahexaenoic AcidsEicosapentaenoic AcidEsterificationFatty Acids, Omega-3Fatty Acids, UnsaturatedFemaleFinlandFishesFish OilsHairDietary FatsDocosahexaenoic Acidsdocosapentaenoic acidEicosapentaenoic AcidFatty Acids, Omega-3Fatty Acids, UnsaturatedFish OilsMercury

Identifiers

PMID25923477
PMCPMC12877651
OpenAlexW2073954274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.