ArticlePLoS neglected tropical diseases2015
A household serosurvey to estimate the magnitude of a dengue outbreak in Mombasa, Kenya, 2013.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.
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Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Quantitative modelling for dengue and Aedes mosquitoes in Africa: A systematic review of current approaches and future directions for Early Warning System development.PLoS neglected tropical diseases · 2024Pooled it
- Dengue Virus Infection and Associated Risk Factors in Africa: A Systematic Review and Meta-Analysis.Viruses · 2021Pooled it
- A decade of dengue disease burden in Africa (2013-2023): a systematic review.Travel medicine and infectious diseasePooled it
- Molecular diagnosis of arboviruses (dengue, Chikungunya, yellow fever, Rift Valley fever, Mayaro, West Nile, and Zika viruses) in non-malaria acute febrile illnesses in Kenya's Garissa County, July 2023, and Mombasa County, July 2024.BMC infectious diseases · 2026Article
- Risk factors associated with dengue and chikungunya seroprevalence and seroconversion among urban populations in western and coastal Kenya.PLoS neglected tropical diseases · 2025Article
- Predicting the ecological niches ofFrontiers in tropical diseases · 2025Article
- Genomic Characterization of Circulating Dengue Virus, Ethiopia, 2022-2023.Emerging infectious diseases · 2025Article
- Vertical transmission of Dengue virus type-3 and metagenomic virome profiles of Aedes aegypti mosquitoes collected in Kisumu, Kenya.PloS one · 2025Article
- Article
- School and home-based educational intervention in urban Kenya: Sustained improvements in knowledge, attitudes, and practices for Aedes aegypti control.PLOS global public health · 2025Article
- Geographic origin and evolution of dengue virus serotypes 1 and 3 circulating in Africa.Virus evolution · 2025Article
- Seroprevalence of dengue, yellow fever, and related flaviviruses among the rural human population in Nguruman and Kerio Valley, Kenya.Frontiers in virology (Lausanne, Switzerland) · 2024Article
- Oviposition Preferences of Aedes aegypti in Msambweni, Kwale County, Kenya.Journal of the American Mosquito Control Association · 2023Article
- Dengue vectors in Africa: A review.Heliyon · 2022Article
- Uncovering the Burden of Dengue in Africa: Considerations on Magnitude, Misdiagnosis, and Ancestry.Viruses · 2022Review
- Urban Ecology of Arboviral Mosquito Vectors Along the Kenyan Coast.Journal of medical entomology · 2021Article
- Clinical and epidemiologic characteristics associated with dengue fever in Mombasa, Kenya.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020Article
- No Evidence of Acute Dengue Virus Infections at a Rural Site in Western Kenya, 2011 and 2013.The American journal of tropical medicine and hygiene · 2020Article
- Risk factors for Aedes aegypti household pupal persistence in longitudinal entomological household surveys in urban and rural Kenya.Parasites & vectors · 2020Article
- Zika Virus Circulates at Low Levels in Western and Coastal Kenya.The Journal of infectious diseases · 2020Article
Corrections and comments
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Authors and funding
19 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue appears to be endemic in Africa with a number of reported outbreaks. In February 2013, several individuals with dengue-like illnesses and negative malaria blood smears were identified in Mombasa, Kenya. Dengue was laboratory confirmed and an investigation was conducted to estimate the magnitude of local transmission including a serologic survey to determine incident dengue virus (DENV) infections. Consenting household members provided serum and were questioned regarding exposures and medical history. RT-PCR was used to identify current DENV infections and IgM anti-DENV ELISA to identify recent infections. Of 1,500 participants from 701 households, 210 (13%) had evidence of current or recent DENV infection. Among those infected, 93 (44%) reported fever in the past month. Most (68, 73%) febrile infected participants were seen by a clinician and all but one of 32 participants who reportedly received a diagnosis were clinically diagnosed as having malaria. Having open windows at night (OR = 2.3; CI: 1.1-4.8), not using daily mosquito repellent (OR = 1.6; CI: 1.0-2.8), and recent travel outside of Kenya (OR = 2.5; CI: 1.1-5.4) were associated with increased risk of DENV infection. This survey provided a robust measure of incident DENV infections in a setting where cases were often unrecognized and misdiagnosed.
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