ArticlePLoS genetics2015
Auxin influx carriers control vascular patterning and xylem differentiation in Arabidopsis thaliana.
Article in PLoS genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 90 citations in OpenAlex.
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- Combining single-cell RNA sequencing with spatial transcriptome analysis reveals dynamic molecular maps of cambium differentiation in the primary and secondary growth of trees.Plant communications · 2023Article
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- Single-nuclei transcriptome analysis of the shoot apex vascular system differentiation in Populus.Development (Cambridge, England) · 2022Article
- Combined use of specific length amplified fragment sequencing (SLAF-seq) and bulked segregant analysis (BSA) for rapid identification of genes influencing fiber content of hemp (Cannabis sativa L.).BMC plant biology · 2022Article
- Fossils and plant evolution: structural fingerprints and modularity in the evo-devo paradigm.EvoDevo · 2022Review
- Computational Models of Auxin-Driven Patterning in Shoots.Cold Spring Harbor perspectives in biology · 2022Review
- Genotype-dependent contribution of CBF transcription factors to long-term acclimation to high light and cool temperature.Plant, cell & environment · 2022Article
- Auxin Transporters-A Biochemical View.Cold Spring Harbor perspectives in biology · 2022Review
- Modeling Auxin Signaling in Roots: Auxin Computations.Cold Spring Harbor perspectives in biology · 2022Review
- CkREV regulates xylem vessel development inFrontiers in plant science · 2022Article
- Auxin controls the division of root endodermal cells.Plant physiology · 2021Article
- Knockout of Auxin Response Factor SlARF4 Improves Tomato Resistance to Water Deficit.International journal of molecular sciences · 2021Article
- Transcriptional control of local auxin distribution by the CsDFB1-CsPHB module regulates floral organogenesis in cucumber.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Decreased Vascular Bundle 1 affects mitochondrial and plant development in rice.Rice (New York, N.Y.) · 2021Article
- IntegratedFrontiers in plant science · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
Abstract
Auxin is an essential hormone for plant growth and development. Auxin influx carriers AUX1/LAX transport auxin into the cell, while auxin efflux carriers PIN pump it out of the cell. It is well established that efflux carriers play an important role in the shoot vascular patterning, yet the contribution of influx carriers to the shoot vasculature remains unknown. Here, we combined theoretical and experimental approaches to decipher the role of auxin influx carriers in the patterning and differentiation of vascular tissues in the Arabidopsis inflorescence stem. Our theoretical analysis predicts that influx carriers facilitate periodic patterning and modulate the periodicity of auxin maxima. In agreement, we observed fewer and more spaced vascular bundles in quadruple mutants plants of the auxin influx carriers aux1lax1lax2lax3. Furthermore, we show AUX1/LAX carriers promote xylem differentiation in both the shoot and the root tissues. Influx carriers increase cytoplasmic auxin signaling, and thereby differentiation. In addition to this cytoplasmic role of auxin, our computational simulations propose a role for extracellular auxin as an inhibitor of xylem differentiation. Altogether, our study shows that auxin influx carriers AUX1/LAX regulate vascular patterning and differentiation in plants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.