ArticleJournal of palliative medicine2015
A Pilot Study To Define Chemical Coping in Cancer Patients Using the Delphi Method.
Article in Journal of palliative medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03161795 (Addressing the Risks of Long-Term Opioid Therapy in Chronic Noncancer Pain), which is not on this map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Addressing the Risks of Long-Term Opioid Therapy in Chronic Noncancer Pain: A National, Multicenter, and Observational Cross-sectional Study in South Korea
Who cites it
23 citing papers in PubMed.
- The Personhood Pentadigm: A transcultural framework for analyzing existential distress in palliative care.International journal of nursing sciences · 2026Article
- Industry Perceptions of Thoroughbred Racehorse Emotions and Quality of Life: Implications for the Development of an Equine Quality of Life Assessment Tool.Animals : an open access journal from MDPI · 2026Article
- Article
- Family perspectives on chemical coping in advanced cancer: influence on opioid-use concerns.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Establishing a common definition for care provided by hospice societies in British Columbia, Canada: a Delphi process.Palliative care and social practice · 2025Article
- A Delphi Study to Determine International and National Equestrian Expert Opinions on Domains and Sub-Domains Essential to Managing Sporthorse Health and Welfare in the Olympic Disciplines.Animals : an open access journal from MDPI · 2023Article
- Ethical considerations in the relief of cancer pain.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Review
- An acceptance and commitment therapy-based intervention for opioid use disorder risk in individuals with cancer: A treatment development study.Journal of contextual behavioral science · 2023Article
- A Survey of Knowledge and Barriers of Healthcare Professionals toward Opioid Analgesics in Cancer Pain Management.International journal of clinical practice · 2022Article
- Factors Influencing Pain Expression in Patients with Cancer: An Expert Opinion.Pain and therapy · 2021Article
- Incidence of and Factors Associated With Nonfatal Self-injury After a Cancer Diagnosis in Ontario, Canada.JAMA network open · 2021Article
- Assessment tools for problematic opioid use in palliative care: A scoping review.Palliative medicine · 2021Article
- Opioid Therapy in Cancer Patients and Survivors at Risk of Addiction, Misuse or Complex Dependency.Frontiers in pain research (Lausanne, Switzerland) · 2021Review
- How Do We Taper and Discontinue Opioids in Cancer Patients? Considerations from the Activities of a Palliative Care Team at a University Hospital.Palliative medicine reports · 2021Article
- Utilization, financial outcomes and stakeholder perspectives of a re-organized adult sickle cell program.PloS one · 2020Article
- A pediatric cancer patient with suspected chemical coping following high-dose opioid therapy: a case report.Journal of medical case reports · 2019Article
- Opioid Prescribing in an Opioid Crisis: What Basic Skills Should an Oncologist Have Regarding Opioid Therapy?Current treatment options in oncology · 2019Review
- Balancing opioid analgesia with the risk of nonmedical opioid use in patients with cancer.Nature reviews. Clinical oncology · 2019Review
- Addressing Opioid-Related Chemical Coping in Long-Term Opioid Therapy for Chronic Noncancer Pain: A Multicenter, Observational, Cross-Sectional Study.Journal of clinical medicine · 2018Article
- Safe Opioid Use: Management of Opioid-Related Adverse Effects and Aberrant Behaviors.Hematology/oncology clinics of North America · 2018Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
background"Chemical coping" is a commonly used term in the pain and palliative care literature, but is heterogeneously defined. We conducted a Delphi survey among palliative care and pain specialists internationally to identify a consensus definition for "chemical coping with opioids" and warning signs for chemical coping.
methodsThis Delphi survey consisted of two rounds on the following: (1) concepts and definition related to chemical coping, (2) warning signs for chemical coping, and (3) demographics. Consensus in this study was defined as agreement by a minimum of 70% of the experts.
resultsParticipating in the first round were 14/19 (74%) physicians; 12/14 (86%) participated in the second round. The international experts reached the following consensus definition for chemical coping with opioids (92% agreement): "The use of opioids to cope with emotional distress, characterized by inappropriate and/or excessive opioid use." They also identified depression (consensus 93%); psychiatric disease (86%); a history of substance abuse (86%); a positive score for the Cut-down, Annoyed, Guilty, and Eye-opener (CAGE) alcoholism screening test (79%); a history of alcoholism (79%); and a history of smoking (71%) as important warning signs for chemical coping.
conclusionOur expert panel reached a consensus definition for chemical coping and related warning signs, which may help clinicians and researchers to identify patients at risk of opioid misuse.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.