Evidence map›Paper›PMID 25922760›Full record

ArticleJournal of ophthalmology2015

Comparison of United States and canadian glaucoma medication costs and price change from 2006 to 2013.

Matthew B Schlenker, Graham E Trope, Yvonne M Buys

Abstract read
In one paragraph

Article in Journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. [Possibilities and limitations of eye drops for glaucoma therapy].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2016
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matthew B SchlenkerDepartment of Ophthalmology & Vision Sciences, University of Toronto, 340 College Street, Suite 400, Toronto, ON, Canada M5T 3A9.
Graham E TropeDepartment of Ophthalmology & Vision Sciences, University of Toronto, 340 College Street, Suite 400, Toronto, ON, Canada M5T 3A9 ; Toronto Western Hospital, East Wing 6-405, Bathurst Street, Toronto, ON, Canada M5T 2S8.
Yvonne M BuysDepartment of Ophthalmology & Vision Sciences, University of Toronto, 340 College Street, Suite 400, Toronto, ON, Canada M5T 3A9 ; Toronto Western Hospital, East Wing 6-405, Bathurst Street, Toronto, ON, Canada M5T 2S8 ; Kensington Eye Institute, 340 College Street, Suite 400, Toronto, ON, Canada M5T 3A9.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective. Compare glaucoma medication costs between the United States (USA) and Canada. Methods. We modelled glaucoma brand name and generic medication annual costs in the USA and Canada based on October 2013 Costco prices and previously reported bottle overfill rates, drops per mL, and wastage adjustment. We also calculated real wholesale price changes from 2006 to 2013 based on the Average Wholesale Price (USA) and the Ontario Drug Benefit Price (Canada). Results. US brand name medication costs were on average 4x more than Canadian medication costs (range: 1.9x-6.9x), averaging a cost difference of $859 annually. US generic costs were on average the same as Canadian costs, though variation exists. US brand name wholesale prices increased from 2006 to 2013 more than Canadian prices (US range: 29%-349%; Canadian range: 9%-16%). US generic wholesale prices increased modestly (US range: -23%-58%), and Canadian wholesale prices decreased (Canadian range: -38%-0%). Conclusions. US brand name glaucoma medications are more expensive than Canadian medications, though generic costs are similar (with some variation). The real prices of brand name medications increased more in the USA than in Canada. Generic price changes were more modest, with real prices actually decreasing in Canada.

Identifiers

PMID25922760
PMCPMC4397467

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.