Evidence map›Paper›PMID 25922672›Full record

ReviewUnited European gastroenterology journal2015

The gluten-free diet and its current application in coeliac disease and dermatitis herpetiformis.

Carolina Ciacci, Paul Ciclitira, Marios Hadjivassiliou, Katri Kaukinen, Jonas F Ludvigsson, Norma McGough, David S Sanders, Jeremy Woodward, Jonathan N Leonard, Gillian L Swift

Open access · bronzeAbstract readReview
In one paragraph

Review in United European gastroenterology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 115 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Therapeutic Potential of White Kidney Beans (Foods (Basel, Switzerland) · 2025
    Review
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 4 countries.

Carolina CiacciDepartment of Medicine and Surgery, Gastroenterology, University of Salerno, Italy.
Paul CiclitiraDepartment of Gastroenterology, Division of Diabetes and Nutritional Sciences, Kings College London; The Rayne Institute, St Thomas Hospital, London, UK.
Marios HadjivassiliouAcademic Department of Neurosciences, Sheffield Teaching Hospitals NHS Trust; Royal Hallamshire Hospital, Sheffield, UK.
Katri KaukinenSchool of Medicine, University of Tampere and Department of Internal Medicine, Tampere University Hospital and Department of Internal Medicine, Seinäjoki Central Hospital, Finland.
Jonas F LudvigssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet and Department of Pediatrics, Örebro University Hospital, Sweden.
Norma McGoughCoeliac UK, High Wycombe, Buckinghamshire, UK.
David S SandersGastroenterology and Liver Unit, Royal Hallamshire Hospital & University of Sheffield, Sheffield, UK.
Jeremy WoodwardCambridge Intestinal Unit, Addenbrooke's Hospital, Cambridge, UK.
Jonathan N LeonardDepartment of Dermatology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
Gillian L SwiftDepartment of Gastroenterology, University Hospital Llandough, Cardiff, UK.
Addenbrooke's Hospital · GBCoeliac UK · GBKing's College London · GBÖrebro University Hospital · SERoyal Hallamshire Hospital · GBSt Mary's Hospital · GBTampere University Hospital · FIUniversity Hospital Llandough · GBUniversity of Salerno · ITUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA gluten-free diet (GFD) is currently the only available therapy for coeliac disease (CD).

objectivesWe aim to review the literature on the GFD, the gluten content in naturally gluten-free (GF) and commercially available GF food, standards and legislation concerning the gluten content of foods, and the vitamins and mineral content of a GFD.

methodsWe carried out a PubMed search for the following terms: Gluten, GFD and food, education, vitamins, minerals, calcium, Codex wheat starch and oats. Relevant papers were reviewed and for each topic a consensus among the authors was obtained.

conclusionPatients with CD should avoid gluten and maintain a balanced diet to ensure an adequate intake of nutrients, vitamins, fibre and calcium. A GFD improves symptoms in most patients with CD. The practicalities of this however, are difficult, as (i) many processed foods are contaminated with gluten, (ii) staple GF foods are not widely available, and (iii) the GF substitutes are often expensive. Furthermore, (iv) the restrictions of the diet may adversely affect social interactions and quality of life. The inclusion of oats and wheat starch in the diet remains controversial.

Indexed as

Coeliac diseasedermatitis herpetiformisgluten freegluten-free dietparts per million

Identifiers

PMID25922672
PMCPMC4406897
OpenAlexW2118257393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.