Evidence map›Paper›PMID 25922575›Full record

ArticleSubstance abuse : research and treatment2015

Lower Cortisol Activity is Associated with First-Time Driving while Impaired.

Sophie Couture, Marie Claude Ouimet, Christina Gianoulakis, Jacques Tremblay, Nmk Ng Ying Kin, Serge Brochu, Jens Pruessner, Katarina Dedovic, Thomas G Brown

Abstract read
In one paragraph

Article in Substance abuse : research and treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sophie CoutureAddiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; School of Criminology, Université de Montréal, Montreal, Quebec, Canada. ; Centre jeunesse de Montréal - Institut universitaire, Montreal, Quebec, Canada.
Marie Claude OuimetFaculty of Medicine and Health Sciences, Université de Sherbrooke, Longueuil, Quebec, Canada.
Christina GianoulakisAddiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
Jacques TremblayAddiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
Nmk Ng Ying KinAddiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
Serge BrochuSchool of Criminology, Université de Montréal, Montreal, Quebec, Canada.
Jens PruessnerDepartment of Psychiatry, McGill University, Montreal, Quebec, Canada.
Katarina DedovicAddiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; Social and Affective Neuroscience Laboratory, University of California, Los Angeles, Los Angeles, USA.
Thomas G BrownAddiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; Department of Psychiatry, McGill University, Montreal, Quebec, Canada. ; Foster Addiction Rehabilitation Centre, St. Philippe de Laprairie, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Driving while impaired (DWI) is a grave and persistent high-risk behavior. Previous work demonstrated that DWI recidivists had attenuated cortisol reactivity compared to non-DWI drivers. This suggests that cortisol is a neurobiological marker of high-risk driving. The present study tested the hypothesis that this initial finding would extend to first-time DWI (fDWI) offenders compared to non-DWI drivers. Male fDWI offenders (n = 139) and non-DWI drivers (n = 31) were exposed to a stress task, and their salivary cortisol activity (total output and reactivity) was measured. Participants also completed questionnaires on sensation seeking, impulsivity, substance use, and engagement in risky and criminal behaviors. As hypothesized, fDWI offenders, compared to non-DWI drivers, had lower cortisol reactivity; fDWI offenders also showed lower total output. In addition, cortisol activity was the most important predictor of group membership, after accounting for alcohol misuse patterns and consequences and other personality and problem behavior characteristics. The findings indicate that attenuated cortisol activity is an independent factor associated with DWI offending risk at an earlier stage in the DWI trajectory than previously detected.

Indexed as

cortisolimpaired drivingneurobiological marker

Identifiers

PMID25922575
PMCPMC4384759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.