Evidence map›Paper›PMID 25922140›Full record

ArticleEuropean journal of pediatrics2015

Comparison of pre- and intrapartum screening of group B streptococci and adherence to screening guidelines: a cohort study.

Mirjam Kunze, Katharina Zumstein, Filiz Markfeld-Erol, Roland Elling, Fabian Lander, Heinrich Prömpeler, Reinhard Berner, Markus Hufnagel

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Rapid tests for detecting group B streptococcus colonization in pregnant women: A systematic review and meta-analysis of diagnostic accuracy.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Pooled it
  2. Pooled it
  3. Maternal Colonization With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Pooled it
  4. Review
  5. Article
  6. Journal of medical microbiology · 2026
    Article
  7. Article
  8. Persistent reduction ofFrontiers in immunology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Prevalence and Clinical Significance ofInfectious diseases in obstetrics and gynecology · 2018
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mirjam KunzeDepartment of Gynecology and Obstetrics, University Medical Center Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany, mirjam.kunze@uniklinik-freiburg.de.
Katharina Zumstein
Filiz Markfeld-Erol
Roland Elling
Fabian Lander
Heinrich Prömpeler
Reinhard Berner
Markus Hufnagel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledImplementation of guidelines for group B streptococcal (GBS) prepartum screening (PS) rarely has been prospectively evaluated. To assess PS at 35-37 weeks of gestation and compare its predictive value to that of an intrapartum screening (IS) within 7 days of delivery, a surveillance cohort study was conducted at a tertiary care center in Freiburg, Germany, during 2011-2012. Study participants included 937 pregnant women who had intrapartum cultures taken for vaginal and rectal GBS colonization. Colonization status was compared to PS, and intrapartum antibiotic prophylaxis (IAP) rates calculated. The neonates were tested for GBS transmission via cultures from their throats and external ear canals. While 67.5% (633/937) of study participants had a PS, only 22.7% (144/633) underwent a fully guideline-compatible PS. However, maternal GBS colonization rates were similar when comparing PS (18.5% [117/633]) versus IS (17.0% [133/784]). The positive predictive value of a positive PS result for GBS positivity at delivery was 77.2 %. Women with a positive PS received IAP in 89.3% of cases (75/84). The capsular serotype distribution pattern of colonizing GBS strains has not changed in comparison to our 2003-2004 study--one with a similar study design.

conclusionsImproved strategies for adoption of prepartum GBS screening are needed. WHAT IS KNOWN: • The prediction of prepartum GBS screening for intrapartum colonization status has not been well studied. • Longitudinal studies of GBS screening are needed for screening program evaluations and vaccine development. What is New: • The rate of GBS screening has improved over 10 years, and intrapartum GBS colonization prediction was accurate. • Serotype distribution was stable and suggests the potential long-term efficacy of GBS vaccines.

Indexed as

AdolescentAdultAnti-Bacterial AgentsAntibiotic ProphylaxisCohort StudiesDelivery, ObstetricFemaleGuideline AdherenceHumansInfant, NewbornMaternal-Fetal ExchangeMiddle AgedPractice Guidelines as TopicPredictive Value of TestsPregnancyRectumAnti-Bacterial Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.