ArticleEpidemiology and infection2015
The epidemiology, microbiology and clinical impact of Shiga toxin-producing Escherichia coli in England, 2009-2012.
Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
71 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.
- Incubation Period of Shiga Toxin-Producing Escherichia coli.Epidemiologic reviews · 2019Pooled it
- Predicting clinical outcome ofMicrobial genomics · 2025Article
- Escherichia coli O157:H7 prevalence in Upper Egypt: impacts on food safety and human Health, with a protection trial using natural antibacterial Piper cubeba.World journal of microbiology & biotechnology · 2025Article
- Shiga Toxin-ProducingMicroorganisms · 2025Article
- Increased detection of Shiga toxin-producingEpidemiology and infection · 2025Article
- Epidemiology of Shiga toxin-producingJournal of medical microbiology · 2025Article
- Farm animal exposure setting impacts hemolytic uremic syndrome risk among Shiga toxin-producingEpidemiology and infection · 2024Article
- Re-analysis of an outbreak of Shiga toxin-producing Escherichia coli O157:H7 associated with raw drinking milk using Nanopore sequencing.Scientific reports · 2024Article
- Animal and environmental risk factors for sporadic Shiga toxin-producing Escherichia coli (STEC) infection in England: a case control study for O157, O26 and other STEC serotypes.Pathogens and global health · 2023Article
- Analysis ofMicrobial genomics · 2023Article
- Haemolytic uraemic syndrome in children England, Wales, Northern Ireland, and Ireland: A prospective cohort study.Epidemiology and infection · 2023Article
- Detection and analysis of Shiga toxin producing and enteropathogenic Escherichia coli in cattle from Tierra del Fuego, Argentina.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Tail-Engineered Phage P2 Enables Delivery of Antimicrobials into Multiple Gut Pathogens.ACS synthetic biology · 2023Article
- Transforming Shiga toxin-producingFrontiers in microbiology · 2023Article
- Occurrence of Shiga toxin-producing Escherichia coli carrying antimicrobial resistance genes in sheep on smallholdings in Bangladesh.Veterinary medicine and science · 2022Article
- Examining the role of person-to-person transmission during a verocytotoxigenic Escherichia coli outbreak in Ontario, Canada.BMC research notes · 2022Article
- Outbreak of STEC O157:H7 linked to a milk pasteurisation failure at a dairy farm in England, 2019.Epidemiology and infection · 2022Article
- Profile and dynamics of infectious diseases: a population-based observational study using multi-source big data.BMC infectious diseases · 2022Observational
- The epidemiology of Shiga toxin-producingEpidemiology and infection · 2022Article
- Epidemiological investigations identified an outbreak of Shiga toxin-producingEpidemiology and infection · 2021Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Between 1 January 2009 and 31 December 2012 in England, a total of 3717 cases were reported with evidence of Shiga toxin-producing E. coli (STEC) infection, and the crude incidence of STEC infection was 1·80/100 000 person-years. Incidence was highest in children aged 1-4 years (7·63/100 000 person-years). Females had a higher incidence of STEC than males [rate ratio (RR) 1·24, P < 0·001], and white ethnic groups had a higher incidence than non-white ethnic groups (RR 1·43, P < 0·001). Progression to haemolytic uraemic syndrome (HUS) was more frequent in females and children. Non-O157 STEC strains were associated with higher hospitalization and HUS rates than O157 STEC strains. In STEC O157 cases, phage type (PT) 21/28, predominantly indigenously acquired, was also associated with more severe disease than other PTs, as were strains encoding stx2 genes. Incidence of STEC was over four times higher in people residing in rural areas than urban areas (RR 4·39, P < 0·001). Exposure to livestock and/or their faeces was reported twice as often in cases living in rural areas than urban areas (P < 0·001). Environmental/animal contact remains an important risk factor for STEC transmission and is a significant driver in the burden of sporadic STEC infection. The most commonly detected STEC serogroup in England was O157. However, a bias in testing methods results in an unquantifiable under-ascertainment of non-O157 STEC infections. Implementation of PCR-based diagnostic methods designed to detect all STEC, to address this diagnostic deficit, is therefore important.
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