Evidence map›Paper›PMID 25920423›Full record

SynthesisEuropean journal of clinical nutrition2015

Nutritional management in patients with chyle leakage: a systematic review.

B R Steven, S Carey

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European journal of clinical nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Chylothorax after adult cardiac surgery: a comprehensive narrative review.General thoracic and cardiovascular surgery · 2026
    Review
  6. Article
  7. Article
  8. Interventional Radiology in Management of Postoperative Chylous Ascites.Interventional radiology (Higashimatsuyama-shi (Japan) · 2025
    Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

B R StevenSchool of Clinical Nutrition, University of Sydney, Sydney, New South Wales, Australia.
S Carey1] School of Clinical Nutrition, University of Sydney, Sydney, New South Wales, Australia [2] Nutrition and Dietetics Department, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTo investigate all the available evidence assessing the effect of nutrition intervention on patients with chyle leakage and its effectiveness at reducing the need for surgical intervention. SUBJECTS/

methodsA systematic review was undertaken of all English language studies using MEDLINE, Cinahl and Web of Science from January 1980 to September 2013. Case series were included because of limited available evidence. Exclusion criteria included animal studies, pediatrics and studies without nutritional intervention. Assessment of study quality was included. Because of the heterogeneity of the data, no meta-analysis was performed.

resultsThirty-one articles were identified for analysis, all of which were retrospective case series studies. The data within these studies were greatly limited. A total of 550 subjects were identified from these studies, 72% of whom had a chyle leak successfully resolved without surgical intervention. However, there was no significant difference between the type of dietary intervention and the rate of resolution (χ(2)=11.14, P=0.08).

conclusionsAlthough there is evidence to suggest that nutrition may have a role in the management of patients with chyle leakage, it is not possible to determine which dietary methods are most effective. More research is required before any guidelines for best practice can be established.

Indexed as

ChylePrecision MedicineAdultAnastomotic LeakCaprylatesDiet, Fat-RestrictedFood, FormulatedHumansLymphatic SystemMalnutritionParaneoplastic SyndromesParenteral Nutrition, TotalTriglyceridesCaprylatestricaprintricaprylintridecanoinTriglyceridestrilaurin

Identifiers

PMID25920423
OpenAlexW2077787792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.