Evidence map›Paper›PMID 25920384›Full record

Trial reportAnnals of emergency medicine2015

Successful Tobacco Dependence Treatment in Low-Income Emergency Department Patients: A Randomized Trial.

Steven L Bernstein, Gail D'Onofrio, June Rosner, Stephanie O'Malley, Robert Makuch, Susan Busch, Michael V Pantalon, Benjamin Toll

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Cessation of Smoking Trial in the Emergency Department: Long-Term Follow-up of a Randomized Controlled Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. A Parental Smoking Cessation Intervention in the Pediatric Emergency Setting: A Randomized Trial.International journal of environmental research and public health · 2020
    Trial
  10. Trial
  11. Trial
  12. A Multicomponent Intervention Including Texting to Promote Tobacco Abstinence in Emergency Department Smokers: A Pilot Study.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2016
    Trial
  13. Article
  14. Article
  15. Evaluation of an emergency department-based approach to reduce subsequent opioid overdoses.Journal of the American College of Emergency Physicians open · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Lung cancer in the emergency department.Emergency cancer care · 2023
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Steven L BernsteinDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT; Yale Cancer Center, New Haven, CT. Electronic address: steven.bernstein@yale.edu.
Gail D'OnofrioDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT.
June RosnerDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT.
Stephanie O'MalleyDepartment of Psychiatry, Yale School of Medicine, New Haven, CT.
Robert MakuchYale School of Public Health, New Haven, CT.
Susan BuschYale School of Public Health, New Haven, CT.
Michael V PantalonDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT.
Benjamin TollDepartment of Psychiatry, Yale School of Medicine, New Haven, CT; Yale Cancer Center, New Haven, CT.
Yale University · USYale Cancer Center · US

Funding

Treating Low-Income Smokers in the Hospital Emergency DepartmentR01CA141479 · NCI · YALE UNIVERSITY · PI BERNSTEIN, STEVEN L · 2010 to 2014
$3.0M
NCI NIH HHS R01 CA141479NCI NIH HHS R01CA141479
6 · The paper itself

Abstract

STUDY

objectiveTobacco use is common among emergency department (ED) patients, many of whom have low income. Our objective is to study the efficacy of an intervention incorporating motivational interviewing, nicotine replacement, and quitline referral for adult smokers in an ED.

methodsThis was a 2-arm randomized clinical trial conducted from October 2010 to December 2012 in a northeastern urban US ED with 90,000 visits per year. Eligible subjects were aged 18 years or older, smoked, and were self-pay or had Medicaid insurance. Intervention subjects received a motivational interview by a trained research assistant, 6 weeks' worth of nicotine patches and gum initiated in the ED, a faxed referral to the state smokers' quitline, a booster call, and a brochure. Control subjects received the brochure, which provided quitline information. The primary outcome was biochemically confirmed tobacco abstinence at 3 months. Secondary endpoints included quitline use.

resultsOf 778 enrolled subjects, 774 (99.5%) were alive at 3 months. The prevalence of biochemically confirmed abstinence was 12.2% (47/386) in the intervention arm versus 4.9% (19/388) in the control arm, for a difference in quit rates of 7.3% (95% confidence interval 3.2% to 11.5%). In multivariable logistic modeling controlling for age, sex, and race or ethnicity, study subjects remained more likely to be abstinent than controls (odds ratio 2.72; 95% confidence interval 1.55 to 4.75).

conclusionAn intensive intervention improved tobacco abstinence rates in low-income ED smokers. Because approximately 20 million smokers, many of whom have low income, visit US EDs annually, these results suggest that ED-initiated treatment may be an effective technique to treat this group of smokers.

Indexed as

Emergency Service, HospitalAdultFemaleHumansMaleMotivational InterviewingPovertyReferral and ConsultationTobacco Use Cessation DevicesTobacco Use DisorderTreatment Outcome

Identifiers

PMID25920384
PMCPMC4819432
OpenAlexW2139094822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.