Evidence map›Paper›PMID 25919759›Full record

ArticlePloS one2015

Latent Tuberculosis Infection and Associated Factors among Health Care Workers in Kigali, Rwanda.

Claude Rutanga, David W Lowrance, John E Oeltmann, Grace Mutembayire, Matt Willis, Claude Bernard Uwizeye, Ruton Hinda, Chitou Bassirou, Steve Gutreuter, Michel Gasana

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Claude RutangaDivision of Tuberculosis and Other Respiratory Communicable Diseases Rwanda Biomedical Centre, Kigali, Rwanda.
David W LowranceDivision of Global HIV/AIDS, Centers for Disease Control and Prevention, Kigali, Rwanda.
John E OeltmannDivision of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, United States of America.
Grace MutembayireDivision of Tuberculosis and Other Respiratory Communicable Diseases Rwanda Biomedical Centre, Kigali, Rwanda.
Matt WillisDivision of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, United States of America.
Claude Bernard UwizeyeDivision of Global HIV/AIDS, Centers for Disease Control and Prevention, Kigali, Rwanda.
Ruton HindaDivision of HIV-AIDS, Sexually Transmitted Infections, and Other Blood Borne Diseases, Rwanda Biomedical Centre, Kigali, Rwanda.
Chitou BassirouDivision of Global HIV/AIDS, Centers for Disease Control and Prevention, Kigali, Rwanda.
Steve GutreuterDivision of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, United States of America.
Michel GasanaDivision of Tuberculosis and Other Respiratory Communicable Diseases Rwanda Biomedical Centre, Kigali, Rwanda.
Rwanda Biomedical Center · RWCenters for Disease Control and Prevention · US

Funding

NCHHSTP CDC HHS U2G PS000643
6 · The paper itself

Abstract

introductionData are limited regarding tuberculosis (TB) and latent TB infection prevalence in Rwandan health facilities.

methodsWe conducted a cross-sectional survey among healthcare workers (HCWs) in Kigali during 2010. We purposively selected the public referral hospital, both district hospitals, and randomly selected 7 of 17 health centers. School workers (SWs) from the nearest willing public schools served as a local reference group. We tested for latent TB infection (LTBI) using tuberculin skin testing (TST) and asked about past TB disease. We assessed risk of LTBI and past history of TB disease associated with hospital employment. Among HCWs, we assessed risk associated with facility type (district hospital, referral hospital, health center), work setting (inpatient, outpatient), and occupation.

resultsAge, gender, and HIV status was similar between the enrolled 1,131 HCWs and 381 SWs. LTBI was more prevalent among HCWs (62%) than SWs (39%). Adjusted odds of a positive TST result were 2.71 (95% CI 2.01-3.67) times greater among HCWs than SWs. Among HCWs, there was no detectable difference between prevalence of LTBI according to facility type, work setting, or occupation.

conclusionHCWs are at greater risk of LTBI, regardless of facility type, work setting, or occupation. The current status of TB infection control practices should be evaluated in the entire workforce in all Rwandan healthcare facilities.

Indexed as

AdultAgedCatchment Area, HealthFemaleHealth FacilitiesHealth PersonnelHumansLatent TuberculosisMaleMiddle AgedOdds RatioRisk FactorsRwandaSchoolsTuberculin TestYoung Adult

Identifiers

PMID25919759
PMCPMC4412475
OpenAlexW2057845723

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.