Evidence map›Paper›PMID 25918912›Full record

ArticleInternational journal of environmental research and public health2015

A concurrent exposure to arsenic and fluoride from drinking water in Chihuahua, Mexico.

Carmen González-Horta, Lourdes Ballinas-Casarrubias, Blanca Sánchez-Ramírez, María C Ishida, Angel Barrera-Hernández, Daniela Gutiérrez-Torres, Olga L Zacarias, R Jesse Saunders, Zuzana Drobná, Michelle A Mendez and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.

  1. [Fluorides in water for consumption in northern and western Mexico].Revista medica del Instituto Mexicano del Seguro Social · 2022
    Pooled it
  2. The Socio-Environmental Impact in the Adjacent Settlements of a Former Foundry.International journal of environmental research and public health · 2025
    Article
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  7. The Development of FeGels (Basel, Switzerland) · 2023
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  9. As andEnvironmental science and pollution research international · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Carmen González-HortaFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua 31125, Mexico. mcgonzalezhorta@hotmail.com.
Lourdes Ballinas-CasarrubiasFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua 31125, Mexico. lourdes.ballinas@gmail.com.
Blanca Sánchez-RamírezFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua 31125, Mexico. bsanche@uach.mx.
María C IshidaFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua 31125, Mexico. mariacishida@gmail.com.
Angel Barrera-HernándezDepartamento de Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Mexico D. F. 07360, Mexico. darkgray@cinvestav.mx.
Daniela Gutiérrez-TorresFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua 31125, Mexico. mc.danielagutierrez@gmail.com.
Olga L ZacariasFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua 31125, Mexico. olga.zacarias@gmail.com.
R Jesse SaundersDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7461, USA. jesse.saunders@unc.edu.
Zuzana DrobnáDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7461, USA. zuzana_drobna@med.unc.edu.
Michelle A MendezDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7461, USA. mmendez@email.unc.edu.
Gonzalo García-VargasFacultad de Medicina, Universidad Juárez del Estado de Durango (UJED), Gómez Palacio, Durango 35050, Mexico. ggarcia.vargas@gmail.com.
Dana LoomisIARC Monographs Section, IARC/WHO, Lyon Cedex 69372, France. loomisd@iarc.fr.
Miroslav StýbloDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7461, USA. miroslav_styblo@med.unc.edu.
Luz M Del RazoDepartamento de Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Mexico D. F. 07360, Mexico. ldelrazo@cinvestav.mx.
Autonomous University of Chihuahua · MXUniversity of North Carolina at Chapel Hill · USInstituto Politécnico Nacional · MXUniversidad Juárez del Estado de Durango · MX

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Environmental Arsenic and Diabetes MellitusR01ES015326 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STYBLO, MIROSLAV · 2008 to 2012
$3.4M
NICHD NIH HHS P2C HD050924NIEHS NIH HHS 5R01 ES015326-02NIEHS NIH HHS P30 ES010126NIEHS NIH HHS R01 ES015326World Health Organization 001
6 · The paper itself

Abstract

Inorganic arsenic (iAs) and fluoride (F-) are naturally occurring drinking water contaminants. However, co-exposure to these contaminants and its effects on human health are understudied. The goal of this study was examined exposures to iAs and F- in Chihuahua, Mexico, where exposure to iAs in drinking water has been associated with adverse health effects. All 1119 eligible Chihuahua residents (>18 years) provided a sample of drinking water and spot urine samples. iAs and F- concentrations in water samples ranged from 0.1 to 419.8 µg As/L and from 0.05 to 11.8 mg F-/L. Urinary arsenic (U-tAs) and urinary F- (U-F-) levels ranged from 0.5 to 467.9 ng As/mL and from 0.1 to 14.4 µg F-/mL. A strong positive correlation was found between iAs and F- concentrations in drinking water (rs = 0.741). Similarly, U-tAs levels correlated positively with U-F- concentrations (rs = 0.633). These results show that Chihuahua residents exposed to high iAs concentrations in drinking water are also exposed to high levels of F-, raising questions about possible contribution of F- exposure to the adverse effects that have so far been attributed only to iAs exposure. Thus, investigation of possible interactions between iAs and F- exposures and its related health risks deserves immediate attention.

Indexed as

AdolescentAdultAgedAged, 80 and overArsenicDrinking WaterFemaleFluoridesGroundwaterHumansMaleMexicoMiddle AgedPhosphatesYoung AdultArsenicDrinking WaterFluoridesfluorophosphatePhosphates

Identifiers

PMID25918912
PMCPMC4454927
OpenAlexW2161378722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.