Evidence map›Paper›PMID 25918644›Full record

Trial reportJournal of obesity2015

Long-term weight maintenance after a 17-week weight loss intervention with or without a one-year maintenance program: a randomized controlled trial.

Tuula Pekkarinen, Jarmo Kaukua, Pertti Mustajoki

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of obesity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00590655 nacompletednot on this map

Effect of Maintenance Programme on the Long Term Weight Reduction in Severely Obese Patients. A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of HelsinkiRan2002 to 2006Enrolled201ConditionsWeight Loss, Morbid ObesityArmsweight loss programme with maintenance programme, weight loss programme
NCT02881684 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Weight Reduction by Aspiration Therapy in Asian Patients With Morbid Obesity

TypeinterventionalSponsorThe University of Hong KongRan2016 to 2018Enrolled15ConditionsObesityArmsAspiration Therapy (AspireAssist®), Lifestyle Therapy
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effects of total diet replacement programs on mental well-being: A systematic review with meta-analyses.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Pooled it
  3. A systematic review of inequalities in the uptake of, adherence to, and effectiveness of behavioral weight management interventions in adults.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Pooled it
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  5. Determinants of weight loss maintenance: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tuula PekkarinenDivision of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Peijas Hospital, Sairaalakatu 1, PL 900, 00029 HUS Vantaa, Finland.
Jarmo KaukuaDivision of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Peijas Hospital, Sairaalakatu 1, PL 900, 00029 HUS Vantaa, Finland ; Sanofi Oy, PL 22, Huopalahdentie 24, 00350 Helsinki, Finland.
Pertti MustajokiDivision of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Peijas Hospital, Sairaalakatu 1, PL 900, 00029 HUS Vantaa, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWeight lost by obese patients is almost always regained over time. Extended treatment may improve maintenance, but solid evidence is lacking. PURPOSE: We determined effectiveness of maintenance therapy after a weight loss program.

methodsTogether 201 patients (mean age 47 years and BMI 42 kg/m(2), 71% women) were randomly assigned to either a 17-week weight loss program followed by a one-year maintenance program or to a weight loss program without subsequent maintenance intervention. The weight loss program included behavior modification and a very-low-calorie diet, and maintenance program behavior modification. The primary outcome measure was percentage of patients with 5% or more weight loss at the end of maintenance (week 69) and one year later (week 121). Secondary outcomes were weight related changes in lifestyle and quality of life.

resultsAt week 69, 52% of the patients with and 44% of those without maintenance program had lost weight ≥5%, P = 0.40, and, at week 121, 33% and 34%, P = 0.77, respectively. At week 121 secondary outcomes did not differ between the groups among those successfully followed up.

conclusionsThis one-year maintenance program was not effective in preventing weight regain in severely obese patients. Trial Registration. This trial is registered under clinicaltrials.gov Identifier: NCT00590655.

Indexed as

Behavior TherapyHealth BehaviorWeight GainWeight LossWeight Reduction ProgramsBody Mass IndexCaloric RestrictionContinuity of Patient CareFemaleHumansMaleMiddle AgedObesity, MorbidPatient ComplianceQuality of LifeSurveys and Questionnaires

Identifiers

PMID25918644
PMCPMC4396554

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.