Evidence map›Paper›PMID 25918427›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2015

Functional connectivity arises from a slow rhythmic mechanism.

Jingfeng M Li, William J Bentley, Abraham Z Snyder, Marcus E Raichle, Lawrence H Snyder

Erratum issuedAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Trial
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  5. Article
  6. Active neural coordination of motor behaviors with internal states.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Article
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  9. Review
  10. Review
  11. Article
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  17. Twitches, Blinks, and Fidgets: Important Generators of Ongoing Neural Activity.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2019
    Review
  18. DC Shifts-fMRI: A Supplement to Event-Related fMRI.Frontiers in computational neuroscience · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jingfeng M LiDepartments of Anatomy and Neurobiology, jing@eye-hand.wustl.edu.ORCID http://orcid.org/0000-0001-6519-3462
William J BentleyDepartments of Anatomy and Neurobiology.
Abraham Z SnyderRadiology, and Neurology, Washington University School of Medicine, St. Louis, MO 63110.
Marcus E RaichleDepartments of Anatomy and Neurobiology, Radiology, and Neurology, Washington University School of Medicine, St. Louis, MO 63110.
Lawrence H SnyderDepartments of Anatomy and Neurobiology.

Funding

FUNCTIONAL CONNECTIVITY IN THE BRAIN: A NEW APPROACHR01MH102471 · NIMH · WASHINGTON UNIVERSITY · PI SNYDER, LAWRENCE H · 2014 to 2018
$1.9M
A MICRO-ELECTRODE STUDY OF OXYGEN-BASED FUNCTIONAL CONNECTIVITYR21MH093858 · NIMH · WASHINGTON UNIVERSITY · PI SNYDER, LAWRENCE H · 2011 to 2012
$418k
NIMH NIH HHS R01 MH102471NIMH NIH HHS R21 MH093858
6 · The paper itself

Abstract

The mechanism underlying temporal correlations among blood oxygen level-dependent signals is unclear. We used oxygen polarography to better characterize oxygen fluctuations and their correlation and to gain insight into the driving mechanism. The power spectrum of local oxygen fluctuations is inversely proportional to frequency raised to a power (1/f) raised to the beta, with an additional positive band-limited component centered at 0.06 Hz. In contrast, the power of the correlated oxygen signal is band limited from ∼ 0.01 Hz to 0.4 Hz with a peak at 0.06 Hz. These results suggest that there is a band-limited mechanism (or mechanisms) driving interregional oxygen correlation that is distinct from the mechanism(s) driving local (1/f) oxygen fluctuations. Candidates for driving interregional oxygen correlation include rhythmic or pseudo-oscillatory mechanisms.

Indexed as

AlgorithmsAnimalsArrhythmias, CardiacBrainBrain MappingElectrodesHeart RateLearningMacacaMagnetic Resonance ImagingNeural PathwaysNormal DistributionOscillometryOxygenPolarographyRestOxygenband-limitedcriticalityoscillationoxygen polarographyresting-state functional connectivity

Identifiers

PMID25918427
PMCPMC4434692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.