Evidence map›Paper›PMID 25918223›Full record

ReviewThe Journal of cell biology2015

Review series: The cell biology of renal filtration.

Rizaldy P Scott, Susan E Quaggin

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed
21.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 341 citations in OpenAlex.

  1. Review
  2. Immuno-positron emission tomography in cardiovascular disease: Advances, challenges, and opportunities.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2026
    Review
  3. Review
  4. Article
  5. Assessment of TMagma (New York, N.Y.) · 2026
    Article
  6. Article
  7. Deletion ofInternational journal of molecular sciences · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. The Life of a Kidney Podocyte.Acta physiologica (Oxford, England) · 2025
    Review
  20. Endothelial metabolic zonation in the vascular network: a spatiotemporal blueprint for angiogenesis.American journal of physiology. Heart and circulatory physiology · 2025
    Review

127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rizaldy P ScottFeinberg School of Medicine, Northwestern University, Chicago, IL 60611 rizaldy.scott@northwestern.edu.
Susan E QuagginFeinberg School of Medicine, Northwestern University, Chicago, IL 60611.
Northwestern University · US

Funding

Exploiting Tie2 Activation for the Treatment of Vascular DiseasesR01HL124120 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI QUAGGIN, SUSAN E. · 2014 to 2017
$1.5M
NHLBI NIH HHS R01 HL124120NHLBI NIH HHS R01HL124120
6 · The paper itself

Abstract

The function of the kidney, filtering blood and concentrating metabolic waste into urine, takes place in an intricate and functionally elegant structure called the renal glomerulus. Normal glomerular function retains circulating cells and valuable macromolecular components of plasma in blood, resulting in urine with just trace amounts of proteins. Endothelial cells of glomerular capillaries, the podocytes wrapped around them, and the fused extracellular matrix these cells form altogether comprise the glomerular filtration barrier, a dynamic and highly selective filter that sieves on the basis of molecular size and electrical charge. Current understanding of the structural organization and the cellular and molecular basis of renal filtration draws from studies of human glomerular diseases and animal models of glomerular dysfunction.

Indexed as

Cell BiologyGlomerular Filtration RateAnimalsHumansKidney Glomerulus

Identifiers

PMID25918223
PMCPMC4411276
OpenAlexW1957808694

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.