Evidence map›Paper›PMID 25917851›Full record

ReviewHead & neck2016

Follicular dendritic cell sarcoma of the head and neck: Case report, literature review, and pooled analysis of 97 cases.

John Pang, Wojciech K Mydlarz, Zhen Gooi, Kevin M Waters, Justin Bishop, James J Sciubba, Young J Kim, Carole Fakhry

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Head & neck, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 69 citations in OpenAlex.

  1. Molecular Characterization of Biphasic Follicular Dendritic Cell Sarcoma.Applied immunohistochemistry & molecular morphology : AIMM · 2026
    Article
  2. Epstein-Barr virusOncology letters · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

John PangDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.
Wojciech K MydlarzDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.
Zhen GooiDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.
Kevin M WatersDepartment of Pathology, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.
Justin BishopDepartment of Pathology, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.
James J SciubbaMilton J. Dance Jr. Head and Neck Cancer Center, Johns Hopkins Head and Neck Surgery, Baltimore, Maryland.
Young J KimDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.
Carole FakhryDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.
Johns Hopkins University · USJohns Hopkins Hospital · USJohns Hopkins Medicine · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
NCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

backgroundFollicular dendritic cell sarcoma (FDCS) is a rare lymphoid neoplasm presenting in the head and neck. There are no pooled analyses of head and neck FDCS cases in the English language literature.

methodsA MEDLINE and PubMed review of cases from 1978 to February 2014 was performed. Demographics, clinicopathologic data, and outcomes were summarized.

resultsWe presented 2 patients and analyzed 97 cases. The mean age was 42.7 years (SD = 16.3 years). Outcomes were available for 76 patients. Tumors ≤4 cm had better disease-free survival (63% vs 28% at 5 years; p = .0282). Locoregional recurrence was significantly less likely with surgery and radiation compared to surgery alone (15% vs 45%; p = .019) and in patients receiving a neck dissection (10% vs 43%; p = .046).

conclusionThis pooled analysis provides the largest sample size of FDCS of the head and neck to date and suggests that radiation and neck dissection may be beneficial to locoregional oncologic control. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2241-E2249, 2016.

Indexed as

AdultDendritic Cell Sarcoma, FollicularDisease-Free SurvivalFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedNeck DissectionNeoplasm Recurrence, LocalTreatment Outcomedendritic cellfollicular dendritic cell sarcoma (FDCS)head and necksarcoma

Identifiers

PMID25917851
PMCPMC4696909
OpenAlexW1588800271

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.