Evidence map›Paper›PMID 25917819›Full record

ArticleArchives of physical medicine and rehabilitation2015

Health-related profiles of people with lower limb loss.

Dagmar Amtmann, Sara J Morgan, Jiseon Kim, Brian J Hafner

4 registry-linked trialsAbstract read
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01750372 completednot on this map

A Client-Based Outcome System for Individuals With Lower Limb Amputation

TypeobservationalSponsorUniversity of WashingtonRan2010 to 2016Enrolled1,572ConditionsAmputation
NCT03722797 terminatednot on this mapstarted 2017, after this paper: background citation

Metabolic Cost and Physical Activity in Sedentary Adults With a Unilateral Transtibial Amputation as Compared to Controls

TypeobservationalSponsorUniversity of DelawareRan2017 to 2022Enrolled3ConditionsAmputeesArmsMetabolic Cost Testing Procedures
NCT03913273 nacompletednot on this mapstarted 2019, after this paper: background citation

Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation

TypeinterventionalSponsorMassachusetts Institute of TechnologyRan2019 to 2025Enrolled14ConditionsAmputationArmsAMI transtibial amputation, Standard transtibial amputation
NCT05082870 nacompletednot on this mapstarted 2021, after this paper: background citation

Using a Psychosocial Transitional Group to Improve Adaptation, Coping and Mental Health Outcomes Following Limb Loss

TypeinterventionalSponsorSunnybrook Health Sciences CentreRan2021 to 2022Enrolled25ConditionsAmputationArmsSupportive-expressive group therapy (SEGT)
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 123 citations in OpenAlex.

  1. Therapeutic benefits of lower limb prostheses: a systematic review.Journal of neuroengineering and rehabilitation · 2023
    Pooled it
  2. A review of user needs to drive the development of lower limb prostheses.Journal of neuroengineering and rehabilitation · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dagmar AmtmannDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA.
Sara J MorganDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA.
Jiseon KimDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA.
Brian J HafnerDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA. Electronic address: bhafner@u.washington.edu.
University of Washington · US

Funding

A Client-Based Outcome System for Individuals with Lower Limb AmputationR01HD065340 · NICHD · UNIVERSITY OF WASHINGTON · PI HAFNER, BRIAN J · 2014 to 2022
$2.7M
A Client-Based Outcome System for Individuals with Lower Limb AmputationU01HD065340 · NICHD · UNIVERSITY OF WASHINGTON · PI HAFNER, BRIAN J · 2010 to 2013
$2.0M
NICHD NIH HHS HD-065340NICHD NIH HHS R01 HD065340NICHD NIH HHS U01 HD065340
6 · The paper itself

Abstract

objectivesTo construct profiles of self-reported health indicators to examine differences and similarities between people with lower limb loss and a normative sample (hereafter called the norm) and to compare health indicators between subgroups based on level and etiology of limb loss.

designSurvey.

settingGeneral community.

participantsAdults with unilateral lower limb loss (N=1091) participated in this study. Eligibility criteria included lower limb loss due to trauma or dysvascular complications and regular use of a prosthesis.

interventionsNot applicable.

main outcome measuresThe Patient-Reported Outcomes Measurement Information System 29-item Health Profile version 1.0 measures physical function, pain interference, fatigue, sleep disturbance, anxiety, depression, and satisfaction with participation in social roles. The norm includes 5239 individuals representative of the U.S. general population in sex, age, race, ethnicity, and education.

resultsPeople with lower limb loss reported statistically significantly worse physical function, pain interference, and satisfaction with participation in social roles and significantly less fatigue than did the norm. People with transfemoral (ie, above-knee) amputation significantly differed in physical function from people with transtibial (ie, below-knee) amputation. Similarly, people with amputation due to trauma and dysvascular etiology significantly differed in physical function and satisfaction with social roles after adjusting for relevant clinical characteristics.

conclusionsPeople with lower limb loss generally report worse physical function, pain interference, and satisfaction with social roles than do the norm. People with dysvascular amputation reported worse physical function and satisfaction with social roles than did people with traumatic amputation. Health indicator profiles are an efficient way of providing clinically meaningful information about numerous aspects of self-reported health in people with lower limb loss.

Indexed as

Health StatusLower ExtremityMental HealthAdultAgedAmputation, SurgicalAmputeesFatigueFemaleHealth Status IndicatorsHumansMaleMiddle AgedPainRecovery of FunctionSelf ReportAmputationArtificial limbsLimb prosthesisOutcome assessment (health care)Quality of lifeRehabilitation

Identifiers

PMID25917819
PMCPMC4519362
OpenAlexW2036494358

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.