ArticleMicrovascular research2015
Feasibility of assessment of conjunctival microvascular hemodynamics in unilateral ischemic stroke.
Article in Microvascular research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 27 citations in OpenAlex.
- Conjunctival Venular Hemodynamic Biomarkers in Glaucoma.Translational vision science & technology · 2025Article
- Conjunctival optical coherence tomography angiography imaging in sickle cell maculopathy.American journal of ophthalmology case reports · 2022Article
- Quantification of Blood Flow Velocity in the Human Conjunctival Microvessels Using Deep Learning-Based Stabilization Algorithm.Sensors (Basel, Switzerland) · 2021Article
- Assessment of the conjunctival microcirculation for patients presenting with acute myocardial infarction compared to healthy controls.Scientific reports · 2021Article
- Quantitative analysis of conjunctival microvasculature imaged using optical coherence tomography angiography.Eye and vision (London, England) · 2019Article
- Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers.Investigative ophthalmology & visual science · 2018Article
- Automated Assessment of Hemodynamics in the Conjunctival Microvasculature Network.IEEE transactions on medical imaging · 2016Article
- Conjunctival and pulmonary hemodynamic properties in sickle cell disease subjects with and without pulmonary hypertension.Clinical case reports · 2015Article
- Changes in Conjunctival Hemodynamics Predict Albuminuria in Sickle Cell Nephropathy.American journal of nephrology · 2015Article
- Conjunctival microvascular alterations in dry eye disease: A comparative study of Sjögren's and non-Sjögren's subtypes.Taiwan journal of ophthalmologyArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Since the internal carotid artery supplies blood to both the eye and the brain, ocular microvascular hemodynamics can be altered due to ischemic stroke. The purpose of the current study was to establish the feasibility of conjunctival microcirculation imaging for detection of inter-ocular differences in microvascular hemodynamics in subjects with unilateral ischemic stroke. Conjunctival microcirculation imaging was performed in both eyes of 15 healthy control subjects and 12 subjects following unilateral ischemic stroke. Diameter and axial blood velocity were measured in multiple conjunctival venules of each eye. A two-way repeated measures analysis of variance was performed to determine the effects of stroke (control vs. stroke) and side of stroke (ipsilateral vs. contralateral) on conjunctival diameter and axial blood velocity. There was no significant main effect of stroke on conjunctival diameter (P=0.7) or conjunctival axial blood velocity (P=0.9). There was no significant main effect of side of stroke on conjunctival diameter (P=0.8), but there was a significant main effect of side of stroke on conjunctival axial blood velocity (P=0.02). There was a significant interaction effect between stroke and side of stroke (P=0.04), indicating that conjunctival axial blood velocity was lower in ipsilateral eyes than in contralateral eyes of stroke subjects. Conjunctival axial blood velocity and internal carotid artery blood velocity were correlated in stroke subjects (r=0.75, P=0.01, N=10). Conjunctival microcirculation imaging is a feasible method to detect inter-ocular differences in microvascular hemodynamics in subjects with unilateral ischemic stroke.
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Registered trials
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