Evidence map›Paper›PMID 25916789›Full record

ArticleIrish journal of medical science2016

Depression and alcohol withdrawal syndrome: is antidepressant therapy associated with lower rates of hospital readmission?

K Schoonover, M C Burton, S A Larson, S S Cha, M I Lapid

Abstract read
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In one paragraph

Article in Irish journal of medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

K SchoonoverDepartment of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. Schoonover.Kimberly@mayo.edu.
M C BurtonDepartment of Medicine, Mayo Clinic, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.
S A LarsonDepartment of Internal Medicine, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555, USA.
S S ChaDivision of Biostatistics, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
M I LapidDepartment of Psychiatry, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Mayo Clinic · USThe University of Texas Medical Branch at Galveston · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol withdrawal syndrome (AWS) is a frequent cause of admission to acute care hospitals and many of these patients have a history of depression.

aimOur objective was to determine if antidepressant use in patients with a history of depression is associated with lower rates of hospital readmission for AWS.

methodsA retrospective study was performed of patients admitted with AWS between January 1, 2006 and December 31, 2008 to an academic tertiary referral hospital.

resultsThree hundred and twenty-two patients were admitted with AWS during the study period. One hundred and sixty-one patients (50 %) had no history of depression, 111 patients (34 %) had a history of depression and antidepressant use, and 50 patients (16 %) had a history of depression and no antidepressant use. There was no significant difference in the number of hospitalizations for AWS between these three groups. Patients with a history of depression on antidepressant medication were more likely to be retired or work disabled compared to the other two groups (p < 0.05). The antidepressant class most commonly used was SSRI (63 %).

conclusionOur study highlights the high frequency of depression and antidepressant use in patients admitted with AWS to an acute care hospital. As alcohol withdrawal is associated with increased morbidity and mortality and depression is common in those with alcohol use disorder, further research is necessary to clarify the optimal treatment of comorbid depression and alcohol use disorder in reducing these revolving door admissions.

Indexed as

AdultAlcohol-Related DisordersAntidepressive AgentsDepressionFemaleHumansMaleMiddle AgedPatient ReadmissionRetrospective StudiesSubstance Withdrawal SyndromeAntidepressive AgentsAlcohol withdrawal syndromeAntidepressant medicationDepressionHospital readmission

Identifiers

PMID25916789
OpenAlexW2036030153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.