Evidence map›Paper›PMID 25916687›Full record

ArticleJournal of feline medicine and surgery2016

Audiogenic reflex seizures in cats.

Mark Lowrie, Claire Bessant, Robert J Harvey, Andrew Sparkes, Laurent Garosi

Open access · hybridAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Epileptic seizures in cats: practical approaches to diagnosis.Journal of feline medicine and surgery · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Reflex Epilepsy.Aging and disease · 2021
    Review
  7. Article
  8. Article
  9. Role of Adenosine in Epilepsy and Seizures.Journal of caffeine and adenosine research · 2020
    Review
  10. Article
  11. Review
  12. Reflex epilepsy: triggers and management strategies.Neuropsychiatric disease and treatment · 2018
    Review
  13. Article
  14. Review
  15. Article
  16. Are some people suffering as a result of increasing mass exposure of the public to ultrasound in air?Proceedings. Mathematical, physical, and engineering sciences · 2016
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mark LowrieDavies Veterinary Specialists, Hitchin, Hertfordshire, UK mll@vetspecialists.co.uk.
Claire BessantInternational Cat Care, Tisbury, Wiltshire, UK.
Robert J HarveyDepartment of Pharmacology, UCL School of Pharmacy, London, UK.
Andrew SparkesInternational Cat Care, Tisbury, Wiltshire, UK.
Laurent GarosiDavies Veterinary Specialists, Hitchin, Hertfordshire, UK.
Animal Free Research UK · GBUniversity College London · GB

Funding

Medical Research Council MR/M013502/1
6 · The paper itself

Abstract

objectivesThis study aimed to characterise feline audiogenic reflex seizures (FARS).

methodsAn online questionnaire was developed to capture information from owners with cats suffering from FARS. This was collated with the medical records from the primary veterinarian. Ninety-six cats were included.

resultsMyoclonic seizures were one of the cardinal signs of this syndrome (90/96), frequently occurring prior to generalised tonic-clonic seizures (GTCSs) in this population. Other features include a late onset (median 15 years) and absence seizures (6/96), with most seizures triggered by high-frequency sounds amid occasional spontaneous seizures (up to 20%). Half the population (48/96) had hearing impairment or were deaf. One-third of cats (35/96) had concurrent diseases, most likely reflecting the age distribution. Birmans were strongly represented (30/96). Levetiracetam gave good seizure control. The course of the epilepsy was non-progressive in the majority (68/96), with an improvement over time in some (23/96). Only 33/96 and 11/90 owners, respectively, felt the GTCSs and myoclonic seizures affected their cat's quality of life (QoL). Despite this, many owners (50/96) reported a slow decline in their cat's health, becoming less responsive (43/50), not jumping (41/50), becoming uncoordinated or weak in the pelvic limbs (24/50) and exhibiting dramatic weight loss (39/50). These signs were exclusively reported in cats experiencing seizures for >2 years, with 42/50 owners stating these signs affected their cat's QoL. CONCLUSIONS AND RELEVANCE: In gathering data on audiogenic seizures in cats, we have identified a new epilepsy syndrome named FARS with a geriatric onset. Further studies are warranted to investigate potential genetic predispositions to this condition.

Indexed as

AnimalsCat DiseasesCatsEpilepsy, ReflexSeizuresSurveys and Questionnaires

Identifiers

PMID25916687
PMCPMC4819795
OpenAlexW2143504513

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.