ArticleThe American journal of gastroenterology2015
Low Prevalence of Colon Polyps in Chronic Inflammatory Conditions of the Colon.
Article in The American journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Proton pump inhibitors and the risk of colorectal cancer: a systematic review and meta-analysis of observational studies.International journal of colorectal disease · 2020Pooled it
- Trends in colorectal cancer screening compliance and incidence among 60- to 74-year-olds in China.Cancer medicine · 2024Article
- Inflammatory Bowel Disease and Risk of Colorectal Polyps: A Nationwide Population-Based Cohort Study From Sweden.Journal of Crohn's & colitis · 2023Article
- The Association between Colorectal Cancer and Colonoscopic Conditions in Saudi Patients: A 10-Year Cross-Sectional-Retrospective Study.Ethiopian journal of health sciences · 2022Article
- Insights into the underlying mechanisms and clinical management of microscopic colitis in relation to other gastrointestinal disorders.Gastroenterology report · 2022Review
- The Meaning of Incidental Goblet Cells at the Gastroesophageal Junction.Digestive diseases and sciences · 2021Article
- European guidelines on microscopic colitis: United European Gastroenterology and European Microscopic Colitis Group statements and recommendations.United European gastroenterology journal · 2021Article
- New polyp image classification technique using transfer learning of network-in-network structure in endoscopic images.Scientific reports · 2021Article
- Association of Colonic Diverticula with Colorectal Adenomas and Cancer.Medicina (Kaunas, Lithuania) · 2021Article
- Can Immune Checkpoint Inhibitors Induce Microscopic Colitis or a Brand New Entity?Inflammatory bowel diseases · 2019Article
- Prevalence and risk factors for colorectal adenomas in patients with ulcerative colitis.United European gastroenterology journal · 2018Article
- Diagnosis and Management of Microscopic Colitis.The American journal of gastroenterology · 2017Review
- An unexpected inverse association between colon adenomas and colitis.The American journal of gastroenterology · 2015Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPrevious studies have reported a low prevalence of colon polyps in patients with microscopic colitis. The aim of the study was to test whether such inverse associations applied to other inflammatory diseases of the colon.
methodsIn a case-control study among 130,204 patients undergoing colonoscopy for the work-up of diarrhea, we compared the prevalence of colon polyps in a case population of patients with inflammatory bowel disease (IBD), microscopic colitis, histologic signs of active colitis, diverticulitis, or ischemic colitis, and in a control population with normal colon mucosa. Case and control subjects were compared using odds ratios and their 95% confidence intervals adjusted for age and sex.
resultsIn 11,176 patients with microscopic colitis, the prevalence of hyperplastic polyps, serrated adenomas, and tubular adenomas were all reduced: odds ratios=0.46 (95% confidence intervals=0.43-0.49), 0.24 (0.19-0.30), and 0.35 (0.33-0.38), respectively. In 4,435 patients with IBD, the corresponding values were: 0.18 (0.15-0.21), 0.24 (0.16-0.35), and 0.18 (0.15-0.21), respectively. In 6,501 patients with histologically active colitis, the corresponding values were: 0.58 (0.53-0.63), 0.57 (0.46-0.70), and 0.63 (0.58-0.68), respectively. No such consistent reduction in polyp prevalence was found in patients with diverticulitis or ischemic colitis.
conclusionsChronic inflammatory conditions of the colon are associated with a decreased prevalence of colon polyps.
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