Evidence map›Paper›PMID 25915941›Full record

ArticlePloS one2015

Physical activity and bone health in schoolchildren: the mediating role of fitness and body fat.

Ana Torres-Costoso, Luis Gracia-Marco, Mairena Sánchez-López, Blanca Notario-Pacheco, Natalia Arias-Palencia, Vicente Martínez-Vizcaíno

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A comparison of the associations between bone health and three different intensities of accelerometer-derived habitual physical activity in children and adolescents: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Pooled it
  2. Association of objectively measured physical activity and bone health in children and adolescents: a systematic review and narrative synthesis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana Torres-CostosoSchool of Nursing and Physiotherapy, University of Castilla La Mancha, Toledo, Spain.
Luis Gracia-MarcoCHERC (Children's Health and Exercise Research Centre) Sport and Health Sciences, University of Exeter, Exeter, United Kingdom; GENUD "Growth, Exercise, Nutrition and Development" Research Group, University of Zaragoza, Zaragoza, Spain.
Mairena Sánchez-LópezSocial and Health Care Research Center, University of Castilla La-Mancha, Cuenca, Spain; Faculty of Education, University of Castilla La Mancha, Ciudad Real, Spain.
Blanca Notario-PachecoSocial and Health Care Research Center, University of Castilla La-Mancha, Cuenca, Spain.
Natalia Arias-PalenciaSocial and Health Care Research Center, University of Castilla La-Mancha, Cuenca, Spain.
Vicente Martínez-VizcaínoSocial and Health Care Research Center, University of Castilla La-Mancha, Cuenca, Spain; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between physical activity (PA) and bone health is well known, although the role of percent body fat (%BF) and fitness as confounders or mediators in this relationship remains uncertain.

objectiveTo examine whether the association between PA and bone mineral content (BMC) is mediated by %BF and cardiorespiratory fitness (CRF).

methodsIn this cross sectional study, BMC, total %BF (by DXA), vigorous PA (VPA), CRF, age and height were measured in 132 schoolchildren (62 boys, aged 8-11 years). ANCOVA was used to test differences in BMC by %BF, CRF and VPA, controlling for different sets of confounders. Simple mediation analyses and serial multiple mediation analyses were fitted to examine whether the relationship between PA and BMC is mediated by %BF and fitness.

resultsChildren with high %BF had higher total body BMC than their peers after controlling for all sets of confounders. Children with good CRF or VPA had significantly less total body BMC after controlling for age and sex but in children with good CRF this inverse relation disappeared after adjusting by %BF. %BF and CRF both act as a full mediator in the association between VPA and BMC, after inclusion of the potential confounders in the models.

conclusionFitness and %BF seem to have a mediator role on the relationship between physical activity and bone mass.

Indexed as

Bone DensityMotor ActivityPhysical FitnessAdipose TissueChildFemaleHumansMale

Identifiers

PMID25915941
PMCPMC4411135

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.