ArticlePloS one2015
Diagnostic Validity of the Generalized Anxiety Disorder - 7 (GAD-7) among Pregnant Women.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05608109 (Project Smash), which is not on this map. Cited by 152 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Project Smash (Social Media Alcohol Session for Health)
Who cites it
152 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Generalized Anxiety Disorder 7-item (GAD-7) and 2-item (GAD-2) scales for detecting anxiety disorders in adults.The Cochrane database of systematic reviews · 2025Pooled it
- Prevalence of Depression or Anxiety During Antepartum Hospitalizations for Obstetric Complications: A Systematic Review and Meta-analysis.Obstetrics and gynecology · 2021Pooled it
- A systematic review of validated screening tools for anxiety disorders and PTSD in low to middle income countries.BMC psychiatry · 2020Pooled it
- The impact of a family-based perinatal intervention on the mental health of adolescent mothers in Perú.Journal of child and adolescent mental health · 2026Trial
- Predictors of benefits and safety events from participation in a lifestyle therapy trial for adults with depression: A secondary analysis of the CALM randomised controlled trial.The Australian and New Zealand journal of psychiatry · 2026Trial
- Adapting and testing a brief intervention to reduce maternal anxiety during pregnancy (ACORN): report of a feasibility randomized controlled trial.BMC psychiatry · 2022Trial
- Trial
- A Mobile Application for Monitoring and Management of Depressed Mood in a Vulnerable Pregnant Population.Psychiatric services (Washington, D.C.) · 2018Trial
- Perinatal anxiety and depression screening and psychiatric care linkage in a regional Korean obstetric setting.Obstetrics & gynecology science · 2026Article
- Detection of Perinatal Mood and Anxiety Symptoms in Patients Presenting in a Specialty Fetal Care Center During Pregnancy.Journal of clinical psychology in medical settings · 2026Article
- A novel digital hybrid care model for maternal mental health: preliminary findings from a matched retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- The generalized anxiety disorder-7 (GAD-7) and its individual- and contextual-level correlates in Chinese adults.BMC psychology · 2026Article
- Early-life exposure to sugar rationing and long-term risk of depression and anxiety: a population-based natural experiment.Molecular psychiatry · 2026Article
- Article
- Low Pregnancy Cortisol and Infant Socioemotional Problems: The Mediating Role of Postpartum Depressive Symptoms.Developmental psychobiology · 2026Article
- A Brief Intervention for the Treatment of Anxiety in Pregnancy: A Pilot Randomized Controlled Trial (The TAP Study).Psychotherapy and psychosomatics · 2026Article
- The relationships between hoarding-related behaviours and disordered eating in a non-clinical adult sample: an exploratory study.BMC psychology · 2026Article
- From childhood malnutrition to adult mental illness: COVID-19 and the hidden legacy of malnutrition.BMJ global health · 2026Article
- Perinatal mental health and reproductive behavior among women in wartime Ukraine: a cohort study protocol.Frontiers in psychiatry · 2026Article
- The role of prenatal stress and maternal trauma responses in predicting children's mental health during war.European journal of psychotraumatology · 2025Article
92 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors.
Funding
Abstract
objectiveGeneralized anxiety disorder (GAD) during pregnancy is associated with several adverse maternal and perinatal outcomes. A reliable and valid screening tool for GAD should lead to earlier detection and treatment. Among pregnant Peruvian women, a brief screening tool, the GAD-7, has not been validated. This study aims to evaluate the reliability and validity of the GAD-7.
methodsOf 2,978 women who attended their first perinatal care visit and had the GAD-7 screening, 946 had a Composite International Diagnostic Interview (CIDI). The Cronbach's alpha was calculated to examine the reliability. We assessed the criterion validity by calculating operating characteristics. The construct validity was evaluated using factor analysis and association with health status on the CIDI. The cross-cultural validity was explored using the Rasch Rating Scale Model (RSM).
resultsThe reliability of the GAD-7 was good (Cronbach's alpha = 0.89). A cutoff score of 7 or higher, maximizing the Youden Index, yielded a sensitivity of 73.3% and a specificity of 67.3%. One-factor structure of the GAD-7 was confirmed by exploratory and confirmatory factor analysis. Concurrent validity was supported by the evidence that higher GAD-7 scores were associated with poor self-rated physical and mental health. The Rasch RSM further confirmed the cross-cultural validity of the GAD-7.
conclusionThe results suggest that the Spanish-language version of the GAD-7 may be used as a screening tool for pregnant Peruvian women. The GAD-7 has good reliability, factorial validity, and concurrent validity. The optimal cutoff score obtained by maximizing the Youden Index should be considered cautiously; women who screened positive may require further investigation to confirm GAD diagnosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.