Evidence map›Paper›PMID 25915490›Full record

ArticlePloS one2015

Pectin-lipid self-assembly: influence on the formation of polyhydroxy fatty acids nanoparticles.

Susana Guzman-Puyol, José Jesús Benítez, Eva Domínguez, Ilker Sefik Bayer, Roberto Cingolani, Athanassia Athanassiou, Antonio Heredia, José Alejandro Heredia-Guerrero

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Susana Guzman-PuyolSmart Materials, Nanophysics, Fondazione Istituto Italiano di Tecnologia (IIT), via Morego 30, 16163, Genoa, Italy.
José Jesús BenítezInstituto de Ciencia de Materiales de Sevilla (ICMS), Centro mixto CSIC-Universidad de Sevilla, Avda. Americo Vespuccio 49, Isla de la Cartuja, E-41092, Sevilla, Spain.
Eva DomínguezInstituto de Hortofruticultura Subtropical y Mediterránea (IHSM) La Mayora, Universidad de Málaga-CSIC, Algarrobo-Costa, E-29750, Málaga, Spain.
Ilker Sefik BayerSmart Materials, Nanophysics, Fondazione Istituto Italiano di Tecnologia (IIT), via Morego 30, 16163, Genoa, Italy.
Roberto CingolaniFondazione Istituto Italiano di Tecnologia (IIT), via Morego 30, 16163, Genoa, Italy.
Athanassia AthanassiouSmart Materials, Nanophysics, Fondazione Istituto Italiano di Tecnologia (IIT), via Morego 30, 16163, Genoa, Italy.
Antonio HerediaDepartamento de Biología Molecular y Bioquímica, IHSM La Mayora, UMA-CSIC, Universidad de Málaga, E-29071, Málaga, Spain.
José Alejandro Heredia-GuerreroSmart Materials, Nanophysics, Fondazione Istituto Italiano di Tecnologia (IIT), via Morego 30, 16163, Genoa, Italy.
Italian Institute of Technology · ITInstituto de Hortofruticultura Subtropical y Mediterránea "La Mayora" · ESUniversidad de Málaga · ESUniversidad de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles, named cutinsomes, have been prepared from aleuritic (9,10,16-trihidroxipalmitic) acid and tomato fruit cutin monomers (a mixture of mainly 9(10),16-dihydroxypalmitic acid (85%, w/w) and 16-hydroxyhexadecanoic acid (7.5%, w/w)) with pectin in aqueous solution. The process of formation of the nanoparticles of aleuritic acid plus pectin has been monitored by UV-Vis spectrophotometry, while their chemical and morphological characterization was analyzed by ATR-FTIR, TEM, and non-contact AFM. The structure of these nanoparticles can be described as a lipid core with a pectin shell. Pectin facilitated the formation of nanoparticles, by inducing their aggregation in branched chains and favoring the condensation between lipid monomers. Also, pectin determined the self-assembly of cutinsomes on highly ordered pyrolytic graphite (HOPG) surfaces, causing their opening and forming interconnected structures. In the case of cutin monomers, the nanoparticles are fused, and the condensation of the hydroxy fatty acids is strongly affected by the presence of the polysaccharide. The interaction of pectin with polyhydroxylated fatty acids could be related to an initial step in the formation of the plant biopolyester cutin.

Indexed as

EsterificationFatty AcidsMembrane LipidsNanoparticlesPalmitic AcidsPectinsSolanum lycopersicumaleuritolic acidcutinFatty AcidsMembrane LipidsPalmitic AcidsPectins

Identifiers

PMID25915490
PMCPMC4411075
OpenAlexW1982258574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.