Evidence map›Paper›PMID 25914909›Full record

SynthesisThe Cochrane database of systematic reviews2015

Hydrogel dressings for treating pressure ulcers.

Jo C Dumville, Nikki Stubbs, Samantha J Keogh, Rachel M Walker, Zhenmi Liu

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 6 pooled it
25.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 6 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Rigid dressings versus soft dressings for transtibial amputations.The Cochrane database of systematic reviews · 2019
    Pooled it
  2. Organisation of health services for preventing and treating pressure ulcers.The Cochrane database of systematic reviews · 2018
    Pooled it
  3. Support surfaces for treating pressure ulcers.The Cochrane database of systematic reviews · 2018
    Pooled it
  4. Dressings and topical agents for treating pressure ulcers.The Cochrane database of systematic reviews · 2017
    Pooled it
  5. Topical phenytoin for treating pressure ulcers.The Cochrane database of systematic reviews · 2017
    Pooled it
  6. Antibiotics and antiseptics for pressure ulcers.The Cochrane database of systematic reviews · 2016
    Pooled it
  7. Trial
  8. Review
  9. Review
  10. Advanced Wound Care Strategies in Patients with NSTIs.Journal of clinical medicine · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jo C DumvilleSchool of Nursing, Midwifery and Social Work, University of Manchester, Manchester, M13 9PL, UK. jo.dumville@manchester.ac.uk.
Nikki Stubbs
Samantha J Keogh
Rachel M Walker
Zhenmi Liu
Griffith University · AUUniversity of Manchester · GBLeeds Community Healthcare NHS Trust · GB

Funding

Department of Health 13/89/08
6 · The paper itself

Abstract

backgroundPressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many different dressing options including hydrogel dressings. A clear and current overview of the current evidence is required to facilitate decision-making regarding dressing use for the treatment of pressure ulcers.

objectivesTo assess the effects of hydrogel dressings on the healing of pressure ulcers in any care setting. SEARCH

methodsWe searched the following databases: the Cochrane Wounds Group Specialised Register (searched 19 June 2014); The Cochrane Central Register of Controlled Trials (CENTRAL; 2014, Issue 5); Ovid MEDLINE (1946 to June Week 2 2014); Ovid MEDLINE (In-Process & Other Non-Indexed Citations, 23 June 2014); Ovid EMBASE (1974 to 20 June 2014); and EBSCO CINAHL (1982 to 18 June 2014). There were no restrictions based on language or date of publication. SELECTION CRITERIA: Published or unpublished randomised controlled trials (RCTs) comparing the effects of hydrogel dressings with alternative wound dressings or no dressing in the treatment of pressure ulcers (stage II or above). DATA COLLECTION AND ANALYSIS: Two review authors independently performed study selection, risk of bias assessment and data extraction. MAIN

resultsWe included eleven studies (523 participants) in this review. Ten studies had two arms and one had three arms that were all relevant to this review. Three studies compared a hydrogel dressing with a basic wound contact dressing; three studies compared a hydrogel dressing with a hydrocolloid dressing; three studies compared a hydrogel dressing with another hydrogel dressing; one study compared a hydrogel dressing with a foam dressing; one study compared a hydrogel dressing with a dextranomer paste dressing and one study compared a hydrogel dressing with a topical treatment (collagenase). Limited data were available for analyses in this review: we conducted no meta-analyses. Where data were available there was no evidence of a difference between hydrogel and alternative treatments in terms of complete wound healing or adverse events. One small study reported that using hydrogel dressings was, on average, less costly than hydrocolloid dressings, but this estimate was imprecise and its methodology was not clear. All included studies were small, had short follow-up times and were at unclear risk of bias. AUTHORS'

conclusionsIt is not clear if hydrogel dressings are more or less effective than other treatments in healing pressure ulcers or if different hydrogels have different effects, Most trials in this field are very small and poorly reported so that risk of bias is unclear.

Indexed as

Bandages, HydrocolloidCollagenasesDextransHumansHydrogelsOintmentsPressure UlcerRandomized Controlled Trials as TopicCollagenasesdextranomerDextransHydrogelsOintments

Identifiers

PMID25914909
PMCPMC10767619
OpenAlexW1815165013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.