ArticleJournal of cardiovascular development and disease
Evidence of Aortopathy in Mice with Haploinsufficiency of
Article in Journal of cardiovascular development and disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 34 citations in OpenAlex.
- Severe Aortic Stenosis and Pre-Excitation Syndrome in Pregnancy-A Multidisciplinary Approach.Diagnostics (Basel, Switzerland) · 2025Article
- Beyond genomic studies of congenital heart defects through systematic modelling and phenotyping.Disease models & mechanisms · 2024Article
- Identification of congenital aortic valve malformations in juvenile natriuretic peptide receptor 2-deficient mice using high-frequency ultrasound.American journal of physiology. Heart and circulatory physiology · 2024Article
- eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling.Disease models & mechanisms · 2024Article
- Clinical Use of Blood Flow Analysis through 4D-Flow Imaging in Aortic Valve Disease.Journal of cardiovascular development and disease · 2023Review
- Increased Proteoglycanases in Pulmonary Valves after Birth Correlate with Extracellular Matrix Maturation and Valve Sculpting.Journal of cardiovascular development and disease · 2023Article
- Genome Editing and Myocardial Development.Advances in experimental medicine and biology · 2023Review
- Translational potential of hiPSCs in predictive modeling of heart development and disease.Birth defects research · 2022Review
- Vitamin B Mitigates Thoracic Aortic Dilation in Marfan Syndrome Mice by Restoring the Canonical TGF-β Pathway.International journal of molecular sciences · 2021Article
- Ventricular Septation and Outflow Tract Development in Crocodilians Result in Two Aortas with Bicuspid Semilunar Valves.Journal of cardiovascular development and disease · 2021Article
- Excess Provisional Extracellular Matrix: A Common Factor in Bicuspid Aortic Valve Formation.Journal of cardiovascular development and disease · 2021Review
- Development of the Human Arterial Valves: Understanding Bicuspid Aortic Valve.Frontiers in cardiovascular medicine · 2021Review
- NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease.Frontiers in cardiovascular medicine · 2021Review
- Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy.Disease models & mechanisms · 2020Article
- Macrophage-derived MMP-8 determines smooth muscle cell differentiation from adventitia stem/progenitor cells and promotes neointima hyperplasia.Cardiovascular research · 2020Article
- Development and evolution of the metazoan heart.Developmental dynamics : an official publication of the American Association of Anatomists · 2019Review
- Abnormal Longitudinal Growth of the Aorta in Children with Familial Bicuspid Aortic Valve.Pediatric cardiology · 2017Article
- Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.JCI insight · 2017Article
- Article
- Pathogenic Mechanisms of Bicuspid Aortic Valve Aortopathy.Frontiers in physiology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Thoracic aortic aneurysms (TAA) are a significant cause of morbidity and mortality in humans. While the exact etiology is unknown, genetic factors play an important role. Mutations in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.