Evidence map›Paper›PMID 25914875›Full record

ReviewChonnam medical journal2015

Comorbidity of depression with physical disorders: research and clinical implications.

Hee-Ju Kang, Seon-Young Kim, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Jin-Sang Yoon, Jae-Min Kim

Open access · hybridAbstract readReview
In one paragraph

Review in Chonnam medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 6 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 6 syntheses or guidelines pooled it, 226 citations in OpenAlex.

  1. Pooled it
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  11. Working hours and depression in the HEAF cohort.Occupational medicine (Oxford, England) · 2025
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  17. Mortality in patients with major depressive disorder: A nationwide population-based cohort study with 11-year follow-up.European psychiatry : the journal of the Association of European Psychiatrists · 2024
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hee-Ju KangDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.
Seon-Young KimMental Health Clinic, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Kyung-Yeol BaeDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.
Sung-Wan KimDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.
Il-Seon ShinDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.
Jin-Sang YoonDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.
Jae-Min KimDepartment of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.
Chonnam National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is prevalent in patients with physical disorders, particularly in those with severe disorders such as cancer, stroke, and acute coronary syndrome. Depression has an adverse impact on the courses of these diseases that includes poor quality of life, more functional impairments, and a higher mortality rate. Patients with physical disorders are at higher risk of depression. This is particularly true for patients with genetic and epigenetic predictors, environmental vulnerabilities such as past depression, higher disability, and stressful life events. Such patients should be monitored closely. To appropriately manage depression in these patients, comprehensive and integrative care that includes antidepressant treatment (with considerations for adverse effects and drug interactions), treatment of the physical disorder, and collaborative care that consists of disease education, cognitive reframing, and modification of coping style should be provided. The objective of the present review was to present and summarize the prevalence, risk factors, clinical correlates, current pathophysiological aspects including genetics, and treatments for depression comorbid with physical disorders. In particular, we tried to focus on severe physical disorders with high mortality rates, such as cancer, stroke, and acute coronary syndrome, which are highly comorbid with depression. This review will enhance our current understanding of the association between depression and serious medical conditions, which will allow clinicians to develop more advanced and personalized treatment options for these patients in routine clinical practice.

Indexed as

DepressionPrognosisRisk factors

Identifiers

PMID25914875
PMCPMC4406996
OpenAlexW2074736258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.