Evidence map›Paper›PMID 25914872›Full record

ArticleInternet interventions2015

Randomized Controlled Trial of the Combined Effects of Web and Quitline Interventions for Smokeless Tobacco Cessation.

Brian G Danaher, Herbert H Severson, Shu-Hong Zhu, Judy A Andrews, Sharon E Cummins, Edward Lichtenstein, Gary J Tedeschi, Coleen Hudkins, Chris Widdop, Ryann Crowley and 1 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Internet interventions, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00820495 (Effectiveness of a Web-Assisted Quitline for Smokeless Tobacco Users), which is not on this map. Cited by 15 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 5 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00820495 phase2completednot on this map

Effectiveness of a Web-Assisted Quitline for Smokeless Tobacco Users

TypeinterventionalSponsorOregon Research InstituteRan2009 to 2012Enrolled1,683ConditionsTobacco Use DisorderArmsWeb + Phone, Web Only, Phone Only, Usual Care
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 5 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Interventions for smokeless tobacco use cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Pooled it
  3. Telephone counselling for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Smokeless tobacco cessation interventions: A systematic review.The Indian journal of medical research · 2018
    Pooled it
  5. Interventions for smokeless tobacco use cessation.The Cochrane database of systematic reviews · 2015
    Pooled it
  6. Randomized Controlled Trial of a Text-Based Smokeless Tobacco Cessation Intervention for Rural and Medically Underserved Communities.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Trial
  7. Trial
  8. Trial
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Effect of Tobacco Control Policies on US Smokeless Tobacco Use: A Structured Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Review
  15. Utility of Responsiveness Theory for Classifying Supportive Behaviors to Enhance Smokeless Tobacco Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Brian G DanaherOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403, USA.
Herbert H SeversonOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403, USA.
Shu-Hong ZhuMoores Cancer Center, University of California, San Diego, 9500 Gilman Drive, MC 0905, La Jolla, CA USA.
Judy A AndrewsOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403, USA.
Sharon E CumminsMoores Cancer Center, University of California, San Diego, 9500 Gilman Drive, MC 0905, La Jolla, CA USA.
Edward LichtensteinOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403, USA.
Gary J TedeschiMoores Cancer Center, University of California, San Diego, 9500 Gilman Drive, MC 0905, La Jolla, CA USA.
Coleen HudkinsOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403, USA.
Chris WiddopOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403, USA.
Ryann CrowleyOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403, USA.
John R SeeleyOregon Research Institute, 1776 Millrace Drive, Eugene, OR 97403, USA.
Oregon Research Institute · USUniversity of California, San Diego · US

Funding

XChew Net--Internet Smokeless Tobacco CessationR01CA084225 · NCI · OREGON RESEARCH INSTITUTE · PI SEVERSON, HERBERT H · 2001 to 2011
$3.5M
NCI NIH HHS R01 CA084225
6 · The paper itself

Abstract

backgroundUse of smokeless tobacco (moist snuff and chewing tobacco) is a significant public health problem but smokeless tobacco users have few resources to help them quit. Web programs and telephone-based programs (Quitlines) have been shown to be effective for smoking cessation. We evaluate the effectiveness of a Web program, a Quitline, and the combination of the two for smokeless users recruited via the Web.

objectivesTo test whether offering both a Web and Quitline intervention for smokeless tobacco users results in significantly better long-term tobacco abstinence outcomes than offering either intervention alone; to test whether the offer of Web or Quitline results in better outcome than a self-help manual only Control condition; and to report the usage and satisfaction of the interventions when offered alone or combined.

methodsSmokeless tobacco users (N= 1,683) wanting to quit were recruited online and randomly offered one of four treatment conditions in a 2×2 design: Web Only, Quitline Only, Web + Quitline, and Control (printed self-help guide). Point-prevalence all tobacco abstinence was assessed at 3- and 6-months post enrollment.

results69% of participants completed both the 3- and 6-month assessments. There was no significant additive or synergistic effect of combining the two interventions for Complete Case or the more rigorous Intent To Treat (ITT) analyses. Significant simple effects were detected, individually the interventions were more efficacious than the control in achieving repeated 7-day point prevalence all tobacco abstinence: Web (ITT, OR = 1.41, 95% CI = 1.03, 1.94,

conclusionCombining Web and Quitline interventions did not result in additive or synergistic effects, as have been found for smoking. Both interventions were more effective than a self-help control condition in helping motivated smokeless tobacco users quit tobacco. Intervention usage and satisfaction were related to the amount intervention content offered. Usage of the Quitline intervention decreased when offered in combination, though rates of helpfulness and recommendations were higher when offered in combination.

trial registrationClinicaltrials.gov NCT00820495; http://clinicaltrials.gov/ct2/show/NCT00820495.

Indexed as

eHealthquitlinesmokeless tobaccotobacco cessationWeb-based intervention

Identifiers

PMID25914872
PMCPMC4405799
OpenAlexW2042069359

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.