Evidence map›Paper›PMID 25914764›Full record

ReviewWorld journal of stem cells2015

Vibration stimuli and the differentiation of musculoskeletal progenitor cells: Review of results in vitro and in vivo.

Jennifer Helen Edwards, Gwendolen Clair Reilly

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of stem cells, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. [Low magnitude whole-body vibration and postmenopausal osteoporosis].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018
    Review
  10. Article
  11. Strain and Vibration in Mesenchymal Stem Cells.International journal of biomaterials · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Osteoporosis and sarcopenia: two diseases or one?Current opinion in clinical nutrition and metabolic care · 2016
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jennifer Helen EdwardsJennifer Helen Edwards, Gwendolen Clair Reilly, Kroto Research Institute and INSIGNEO Institute for in silico Medicine, Department of Materials Science and Engineering, University of Sheffield, S1 3JD Sheffield, United Kingdom.
Gwendolen Clair ReillyJennifer Helen Edwards, Gwendolen Clair Reilly, Kroto Research Institute and INSIGNEO Institute for in silico Medicine, Department of Materials Science and Engineering, University of Sheffield, S1 3JD Sheffield, United Kingdom.
Insigneo · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the increasing burden on healthcare budgets of musculoskeletal system disease and injury, there is a growing need for safe, effective and simple therapies. Conditions such as osteoporosis severely impact on quality of life and result in hundreds of hours of hospital time and resources. There is growing interest in the use of low magnitude, high frequency vibration (LMHFV) to improve bone structure and muscle performance in a variety of different patient groups. The technique has shown promise in a number of different diseases, but is poorly understood in terms of the mechanism of action. Scientific papers concerning both the in vivo and in vitro use of LMHFV are growing fast, but they cover a wide range of study types, outcomes measured and regimens tested. This paper aims to provide an overview of some effects of LMHFV found during in vivo studies. Furthermore we will review research concerning the effects of vibration on the cellular responses, in particular for cells within the musculoskeletal system. This includes both osteogenesis and adipogenesis, as well as the interaction between MSCs and other cell types within bone tissue.

Indexed as

Adipogenesis, osteoporosisLow magnitude, high frequency vibration loadingMechanobiologyMesenchymal stem cellsOsteogenesisWhole body vibration

Identifiers

PMID25914764
PMCPMC4404392
OpenAlexW1986455833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.