Evidence map›Paper›PMID 25914472›Full record

ArticleWorld journal of gastroenterology2015

Adjuvant transarterial chemoembolization after curative resection of hepatocellular carcinoma: propensity score analysis.

Jing-Hang Jiang, Zhe Guo, Hao-Feng Lu, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Ri-Rong Yang and 1 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 53 citations in OpenAlex.

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  12. [Research progress of adjuvant TACE therapy for liver cancer after radical resection].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Review
  13. Efficacy of Postoperative Adjuvant Transcatheter Arterial Chemoembolization in Hepatocellular Carcinoma Patients with Mesenchymal Circulating Tumor Cell.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jing-Hang JiangJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Zhe GuoJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Hao-Feng LuJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Xiao-Bo WangJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Hao-Jie YangJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Fu-Quan YangJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Si-Yang BaoJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Jian-Hong ZhongJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Le-Qun LiJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Ri-Rong YangJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Bang-De XiangJing-Hang Jiang, Zhe Guo, Xiao-Bo Wang, Hao-Jie Yang, Fu-Quan Yang, Si-Yang Bao, Jian-Hong Zhong, Le-Qun Li, Bang-De Xiang, Department of Hepatobiliary Surgery, Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
First People’s Hospital of Jingmen · CNFirst People's Hospital of Jingzhou · CNGuangxi Medical University · CNTumor Hospital of Guangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare survival and recurrence in hepatocellular carcinoma (HCC) patients who did or did not receive adjuvant transarterial chemoembolization (TACE).

methodsA consecutive sample of 229 patients who underwent curative resection between March 2007 and March 2010 in our hospital was included. Of these 229 patients, 91 (39.7%) underwent curative resection followed by adjuvant TACE and 138 (60.3%) underwent curative resection alone. In order to minimize confounds due to baseline differences between the two patient groups, comparisons were conducted between propensity score-matched patients. Survival data and recurrence rates were compared using the Kaplan-Meier method. Independent predictors of overall survival and recurrence were identified using Cox proportional hazard regression.

resultsAmong 61 pairs of propensity score-matched patients, the 1-, 2-, and 3-year overall survival rates were 95.1%, 86.7%, and 76.4% in the TACE group and 86.9%, 78.5%, and 73.2% in the control group, respectively. At the same time, the TACE and control groups also showed similar recurrence rates at 1 year (13.4% vs 24.8%), 2 years (30.6% vs 32.1%), and 3 years (40.1% vs 34.0%). Multivariate Cox regression identified serum alpha-fetoprotein level ≥ 400 ng/mL and tumor size > 5 cm as independent risk factors of mortality (P < 0.05).

conclusionAs postoperative adjuvant TACE does not improve overall survival or reduce recurrence in HCC patients, further study is needed to clarify its clinical benefit.

Indexed as

Chemoembolization, TherapeuticHepatectomyAdultalpha-FetoproteinsCarcinoma, HepatocellularChemotherapy, AdjuvantChinaChi-Square DistributionDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateLiver NeoplasmsMaleMiddle AgedMultivariate AnalysisAFP protein, humanalpha-FetoproteinsCurative resectionHepatocellular carcinomaOverall survivalRecurrenceTransarterial chemoembolization

Identifiers

PMID25914472
PMCPMC4402310
OpenAlexW2408627188

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.