Can inflammation regulate systemic aging?

Priyanshi Patel, Richard F Lockey, Narasaiah Kolliputi

Abstract readComment

In one paragraph

Article in Experimental gerontology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside.Molecular neurobiology · 2022
Review
IGF1 Gene Therapy Modifies Microglia in the Striatum of Senile Rats.Frontiers in aging neuroscience · 2019
Article
Resveratrol as a Natural Autophagy Regulator for Prevention and Treatment of Alzheimer's Disease.Nutrients · 2017
Review
Biosystems Study of the Molecular Networks Underlying Hippocampal Aging Progression and Anti-aging Treatment in Mice.Frontiers in aging neuroscience · 2017
Article
Dietary Phytochemicals in Neuroimmunoaging: A New Therapeutic Possibility for Humans?Frontiers in pharmacology · 2016
Review

4 · The record

Corrections and comments

Comment on
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH.2013

5 · Who and what money

Authors and funding

3 authors.

Priyanshi PatelDivision of Allergy and Immunology, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., Tampa, FL 33612, United States.

Richard F LockeyDivision of Allergy and Immunology, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., Tampa, FL 33612, United States.

Narasaiah KolliputiDivision of Allergy and Immunology, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., Tampa, FL 33612, United States. Electronic address: nkollipu@health.usf.edu.

Funding

Molecular Mechanisms of Hyperoxic Lung InjuryR01HL105932 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI KOLLIPUTI, NARASAIAH · 2011 to 2019

$2.9M

NHLBI NIH HHS R01 HL105932

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingAnimalsFemaleGonadotropin-Releasing HormoneHypothalamusI-kappa B KinaseMaleNF-kappa BGonadotropin-Releasing HormoneI-kappa B KinaseNF-kappa BAgingGnRHIκB kinase-β (IKK-β)Nuclear factor κB (NF-κB)

Identifiers

PMID25914111

DOI10.1016/j.exger.2015.04.011

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.