ArticleCurrent opinion in virology2015
The history and market impact of CRISPR RNA-guided nucleases.
Article in Current opinion in virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Methods of crop improvement and applications towards fortifying food security.Frontiers in genome editing · 2023Review
- Uncertainty-aware and interpretable evaluation of Cas9-gRNA and Cas12a-gRNA specificity for fully matched and partially mismatched targets with Deep Kernel Learning.Nucleic acids research · 2022Article
- The Emergence of Genome Editing-Innovation Network Dynamics of Academic Publications, Patents, and Business Activities.Frontiers in bioengineering and biotechnology · 2022Article
- The CRISPR revolution and its potential impact on global health security.Pathogens and global health · 2021Review
- Advances in Genetic Engineering Technology and Its Application in the Industrial FungusFrontiers in microbiology · 2021Review
- Novel genetic therapeutic approaches for modulating the severity of β-thalassemia (Review).Biomedical reports · 2020Review
- The Ethics of Gene Editing from an Islamic Perspective: A Focus on the Recent Gene Editing of the Chinese Twins.Science and engineering ethics · 2020Article
- Bioethical issues in genome editing by CRISPR-Cas9 technology.Turkish journal of biology = Turk biyoloji dergisi · 2020Article
- CRISPR/Cas9 genome editing technology in filamentous fungi: progress and perspective.Applied microbiology and biotechnology · 2019Review
- Modern Trends in Plant Genome Editing: An Inclusive Review of the CRISPR/Cas9 Toolbox.International journal of molecular sciences · 2019Review
- Normative Criteria and Their Inclusion in a Regulatory Framework for New Plant Varieties Derived From Genome Editing.Frontiers in bioengineering and biotechnology · 2018Review
- Use of CRISPR systems in plant genome editing: toward new opportunities in agriculture.Emerging topics in life sciences · 2017Article
- CRISPR/Cas system for yeast genome engineering: advances and applications.FEMS yeast research · 2017Review
- Conformational regulation of CRISPR-associated nucleases.Current opinion in microbiology · 2017Review
- The emerging patent landscape of CRISPR-Cas gene editing technology.Nature biotechnology · 2016Article
- Programmed Self-Assembly of an Active P22-Cas9 Nanocarrier System.Molecular pharmaceutics · 2016Article
- Diversity of CRISPR-Cas immune systems and molecular machines.Genome biology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The interface between viruses and their hosts' are hot spots for biological and biotechnological innovation. Bacteria use restriction endonucleases to destroy invading DNA, and industry has exploited these enzymes for molecular cut-and-paste reactions that are central to many recombinant DNA technologies. Today, another class of nucleases central to adaptive immune systems that protect bacteria and archaea from invading viruses and plasmids are blazing a similar path from basic science to profound biomedical and industrial applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.