Evidence map›Paper›PMID 25913613›Full record

ArticleTrends in microbiology2015

Novel role of DNA in neutrophil extracellular traps.

Christoph Georg Baums, Maren von Köckritz-Blickwede

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Christoph Georg BaumsInstitute for Bacteriology and Mycology, Centre for Infectious Diseases, College of Veterinary Medicine, University Leipzig, An den Tierkliniken 29, 04103 Leipzig, Germany.
Maren von Köckritz-BlickwedeDepartment of Physiological Chemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany. Electronic address: mkoeckbl@tiho-hannover.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophil extracellular traps (NETs) have been shown to play a crucial role in health and disease. In a recent paper in PLoS Pathogens, Halverson et al. demonstrate that the DNA backbone of NETs contributes to its antibacterial activity and serves as signal for entrapped microbes to employ immune evasion strategies.

Indexed as

AnimalsAnti-Infective AgentsDNAExtracellular TrapsHumansNeutrophilsAnti-Infective AgentsDNAantimicrobial activityDNAneutrophilsPseudomonas aeruginosaStaphylococcus aureus

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.