ArticlePsychological medicine2015
Affective modulation of the startle response among children at high and low risk for anxiety disorders.
Article in Psychological medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Startle to neutral, not negative stimuli: A neurophysiological correlate of behavioral inhibition in young children.Developmental psychobiology · 2021Article
- Wearable sensors detect childhood internalizing disorders during mood induction task.PloS one · 2018Article
- The Stony Brook Temperament Study: Early Antecedents and Pathways to Emotional Disorders.Child development perspectives · 2017Article
- Movements Indicate Threat Response Phases in Children at Risk for Anxiety.IEEE journal of biomedical and health informatics · 2017Article
- Impact of anxiety symptoms and problematic alcohol use on error-related brain activity.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017Article
- Error-related brain activity is related to aversive potentiation of the startle response in children, but only the ERN is associated with anxiety disorders.Emotion (Washington, D.C.) · 2017Article
- Anxiety and Depression Symptom Dimensions Demonstrate Unique Relationships with the Startle Reflex in Anticipation of Unpredictable Threat in 8 to 14 Year-Old Girls.Journal of abnormal child psychology · 2017Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIdentifying early markers of risk for anxiety disorders in children may aid in understanding underlying mechanisms and informing prevention efforts. Affective modulation of the startle response indexes sensitivity to pleasant and unpleasant environmental contexts and has been shown to relate to anxiety, yet the extent to which abnormalities in affect-modulated startle reflect vulnerability for anxiety disorders in children has yet to be examined. The current study assessed the effects of parental psychopathology on affective modulation of startle in offspring.
methodNine-year-old children (n = 144) with no history of anxiety or depressive disorders completed a passive picture viewing task in which eye-blink startle responses were measured during the presentation of pleasant, neutral, and unpleasant images.
resultsMaternal anxiety was associated with distinct patterns of affective modulation of startle in offspring, such that children with maternal histories of anxiety showed potentiation of the startle response while viewing unpleasant images, but not attenuation during pleasant images, whereas children with no maternal history of anxiety exhibited attenuation of the startle response during pleasant images, but did not exhibit unpleasant potentiation - even when controlling for child symptoms of anxiety and depression. No effects of maternal depression or paternal psychopathology were observed.
conclusionsThese findings suggest that both enhanced startle responses in unpleasant conditions and failure to inhibit startle responses in pleasant conditions may reflect early emerging vulnerabilities that contribute to the later development of anxiety disorders.
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