Evidence map›Paper›PMID 25913220›Full record

ReviewFrontiers in neuroendocrinology2015

Neuroendocrine control of the onset of puberty.

Tony M Plant

Abstract readReview
In one paragraph

Review in Frontiers in neuroendocrinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Article
  2. Genetics of Idiopathic Hypogonadotropic HypogonadismJournal of clinical research in pediatric endocrinology · 2026
    Review
  3. Review
  4. Review
  5. Leptin Acts as a Peripheral Tropic Signal to Tune Steroidogenesis.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. A hormone-to-neuropeptide pathway inhibits sexual receptivity in immatureProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Puberty Blocker and Aging Impact on Testicular Cell States and Function.bioRxiv : the preprint server for biology · 2024
    Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Tony M PlantDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine and Magee-Womens Research Institute, USA. Electronic address: planttm@mwri.magee.edu.

Funding

Xenografting and Organ Culture of Testicular Tissue: Two Novel Tools to Study PRU54HD008610 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI POHL, CLIFFORD R · 2000 to 2010
$11.5M
THE ONTOGENY OF GONADOTROPIN SECRETION IN THE MONKEYR01HD013254 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PLANT, TONY M · 1985 to 2009
$3.1M
CORE--THE PRIMATE COREP30HD008610 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI POHL, CLIFFORD R · 1985 to 1999
–
NICHD NIH HHS HD 08610NICHD NIH HHS HD 13254NICHD NIH HHS P30 HD008610NICHD NIH HHS R01 HD013254NICHD NIH HHS U54 HD008610
6 · The paper itself

Abstract

This chapter is based on the Geoffrey Harris Memorial Lecture presented at the 8th International Congress of Neuroendocrinology, which was held in Sydney, August 2014. It provides the development of our understanding of the neuroendocrine control of puberty since Harris proposed in his 1955 monograph (Harris, 1955) that "a major factor responsible for puberty is an increased rate of release of pituitary gonadotrophin" and posited "that a neural (hypothalamic) stimulus, via the hypophysial portal vessels, may be involved." Emphasis is placed on the neurobiological mechanisms governing puberty in highly evolved primates, although an attempt is made to reverse translate a model for the timing of puberty in man and monkey to non-primate species.

Indexed as

AnimalsGonadotropin-Releasing HormoneHumansHypothalamusNeuroendocrinologyNeurosecretory SystemsPituitary GlandPubertyGonadotropin-Releasing HormoneGnRH pulse generationGnRH surge generationHumanKisspeptinPubertyRatRhesus monkeySheep

Identifiers

PMID25913220
PMCPMC4457677

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.