Evidence map›Paper›PMID 25912856›Full record

ReviewProgress in neuro-psychopharmacology & biological psychiatry2016

Stress is a principal factor that promotes tobacco use in females.

Oscar V Torres, Laura E O'Dell

Open access · greenAbstract readReview
In one paragraph

Review in Progress in neuro-psychopharmacology & biological psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 163 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Reasons for smoking relapse according to time since quit attempt.Respiratory research & clinical practice · 2026
    Article
  11. Financial Stress and Tobacco Expenditure in Australian Households: A Cross-Sectional Analysis of Prevalence and Association Across Wealth and Income Levels.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  12. Review
  13. Lifestyle medicine pillars for women's heart health.American journal of preventive cardiology · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Oscar V TorresMolecular Neuropsychiatry Research Branch, DHHS/NIH/NIDA Intramural Research Program National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD 21224.
Laura E O'DellDepartment of Psychology, The University of Texas at El Paso, El Paso, TX 79902, USA. Electronic address: lodell@utep.edu.
The University of Texas at El Paso · USUnited States Department of Health and Human Services · US

Funding

TCCG12MD007592 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI KIRKEN, ROBERT A. · 2012 to 2018
$19.4M
Sex Differences in the Mechanisms that Promote Nicotine Reward and WithdrawalR01DA021274 · NIDA · UNIVERSITY OF TEXAS EL PASO · PI ODELL, LAURA ELENA · 2007 to 2019
$4.4M
UTEP DIDARP: Vulnerability Issues in Drug Abuse (VIDA)R24DA029989 · NIDA · UNIVERSITY OF TEXAS EL PASO · PI CASTANEDA, EDWARD · 2011 to 2015
$2.1M
Summer Mentoring And Research Training: Methods In Neuroscience of Drug-abuse (SMART-MIND)R25DA033613 · NIDA · UNIVERSITY OF TEXAS EL PASO · PI Karina C Canaba, LAURA ELENA ODELL · 2012 to 2026
$1.5M
NIDA NIH HHS R01 DA021274NIDA NIH HHS R01-DA021274NIDA NIH HHS R24 DA029989NIDA NIH HHS R24-DA029989NIDA NIH HHS R25 DA033613NIDA NIH HHS R25-DA033613NIMHD NIH HHS G12 MD007592NIMHD NIH HHS G12MD007592
6 · The paper itself

Abstract

Tobacco use is a major economic and health problem. It is particularly concerning that women consume more tobacco products, have a more difficult time quitting smoking, and are less likely to benefit from smoking cessation therapy than men. As a result, women are at higher risk of developing tobacco-related diseases. Clinical evidence suggests that women are more susceptible to anxiety disorders, and are more likely to smoke in order to cope with stress than men. During smoking abstinence, women experience more intense anxiety than men and report that the anxiety-reducing effects of smoking are the main reason for their continued tobacco use and relapse. Consistent with this, pre-clinical studies using rodent models suggest that females display more intense stress during nicotine withdrawal than males. This review posits that in women, stress is a principal factor that promotes the initiation of tobacco use and relapse behavior during abstinence. Studies are reviewed at both the clinical and pre-clinical levels to provide support for our hypothesis that stress plays a central role in promoting tobacco use vulnerability in females. The clinical implications of this work are also considered with regard to treatment approaches and the need for more research to help reduce health disparities produced by tobacco use in women.

Indexed as

AnimalsFemaleHumansSex CharacteristicsStress, PsychologicalTobacco Use Disorderdependencenicotinesex differenceswithdrawalwomen

Identifiers

PMID25912856
PMCPMC4618274
OpenAlexW2042212998

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.