Evidence map›Paper›PMID 25912713›Full record

ArticleViruses2015

Serological evidence of hantavirus infection in apparently healthy people from rural and slum communities in southern Chile.

Claudia Muñoz-Zanzi, Farides Saavedra, Carola Otth, Ljubica Domancich, Melissa Hott, Paula Padula

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  8. Seroprevalence of rodent-borne viruses in Afro-descendent communities in Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Claudia Muñoz-ZanziDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S. Second Street, suite 300, Minneapolis, MN 55454, USA. munozzan@umn.edu.
Farides SaavedraInstitute of Clinical Microbiology, Austral University of Chile, Campus Isla Teja, P.O. Box 567, Valdivia, Chile. farides.saavedra@gmail.com.
Carola OtthInstitute of Clinical Microbiology, Austral University of Chile, Campus Isla Teja, P.O. Box 567, Valdivia, Chile. cotth@uach.cl.
Ljubica DomancichInstitute of Clinical Microbiology, Austral University of Chile, Campus Isla Teja, P.O. Box 567, Valdivia, Chile. ljubica.domancich@gmail.com.
Melissa HottInstitute of Clinical Microbiology, Austral University of Chile, Campus Isla Teja, P.O. Box 567, Valdivia, Chile. melissahottogalde@hotmail.com.
Paula PadulaNational Institute of Infectious Diseases, ANLIS Dr. Carlos G. Malbran, Velez Sarsfield 563 CABA (1281), Buenos Aires 1281, Argentina. ppadula@gmail.com.
Austral University of Chile · CLAdministración Nacional de Laboratorios e Institutos de Salud · ARUniversity of Minnesota · US

Funding

Community Structure and the Epidemiology of Hantavirus in Southern ChileR03AI097672 · NIAID · UNIVERSITY OF MINNESOTA · PI MUNOZ-ZANZI, CLAUDIA · 2012 to 2013
$141k
NIAID NIH HHS 1R03AI097672-01A1NIAID NIH HHS R03 AI097672
6 · The paper itself

Abstract

Hantavirus disease in America has been recognizable because of its rapid progression in clinical cases, occurrence in previously healthy young adults, and high case fatality rate. Hantavirus disease has been proposed now to define the diversity of clinical manifestations. Since 1995, a total of 902 cases of hantavirus pulmonary syndrome have been reported in Chile, caused by Andes virus (ANDV), with overall fatality of 32%. This report describes the sero-epidemiology of hantavirus in apparently healthy people in rural and urban slum communities from southern Chile. Ten of 934 samples yielded a positive result resulting in a seroprevalence of 1.07% (95% confidence intervals: 0.05%-2.0%). A higher proportion of positive samples was found among individuals from rural villages (1.3%) and slums (1.5%) compared with farms (0.5%). Seropositivity was associated with age (p = 0.011), low education level (p = 0.006) and occupations linked to the household (homemaker, retired, or student) (p = 0.016). No evidence of infection was found in 38 sigmodontinae rodents trapped in the peri-domestic environment. Our findings highlight that exposure risk was associated with less documented risk factors, such as women in slum and rural villages, and the occurrence of infection that may have presented as flu-like illness that did not require medical attention or was misdiagnosed.

Indexed as

AdolescentAdultAgedAnimalsAntibodies, ViralChileFemaleHantavirus InfectionsHumansMaleMiddle AgedPoverty AreasRisk FactorsRodentiaRural PopulationSeroepidemiologic StudiesAntibodies, Viral

Identifiers

PMID25912713
PMCPMC4411687
OpenAlexW2098244354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.